Doğum sonrası hipokalsemi şekillenen inekler ile buzağıları arsında kalsiyum, fosfor ve alkalen fosfataz seviyeleri ilişkilerinin araştırılması

Bu çalışmada, doğum sonrası hipokalsemi ile seyreden doğum felci teşhisi konmuş süt inekleri ve doğan yavruları arasındaki Ca, P ve ALP kan serum parametreleri arasındaki ilişkinin araştırılması amaçlanmıştır. Araştırmada materyal olarak, Elazığ ili merkez köylerinde halk elinde bulunan 20 adet değişik ırklara mensup (Holstein, Jersey, Simental, Esmer ve bu ırkların melezleri), ekstansif yetiştirme uygulanan hipokalsemili inek ve bunların buzağıları; ayrıca, 10 adet normal doğum yapmış, sağlıklı, değişik ırklara mensup ekstansif yetiştirme uygulanan kontrol grubu inek ve bunların buzağıları kullanıldı. Tüm hasta hayvanların tedavisinde, kalsiyum (Vetacalsin® Richter Pharma-Avusturya), fosfor (Fosfocure Forte® Provet-Türkiye) ve vitamin AD3EC (Richtasol® Richter Pharma-Avusturya) preparatları kullanıldı. Hipokalsemili ineklerden tedavi öncesi ve tedaviden 1 saat sonra, hasta ineklerin buzağılarından anneye uygulanacak olan tedaviden önce, kontrol grubu inekler ve bunların buzağılarından vena jugularis’ten Ca, P ve ALP düzeyleri ölçülmek üzere 10 ml kan örneği alındı. Hipokalsemili ineklerin tedavi öncesi ortalama Ca, P ve ALP serum değerleri sırasıyla 4.88±020 mg/dl, 2.40±0.25 mg/dl ve 56.46±2.20 U/L, kontrol grubundaki ineklerin ortalama Ca, P ve ALP serum değerleri sırasıyla 8.65±033 mg/dl, 4.71±029 mg/dl ve 48.30±2.41 U/L olarak bulundu. Hipokalsemili ineklerin tedavi öncesi ile kontrol grubu ineklerin Ca, P ve ALP serum değerleri karşılaştırıldığında, Ca ve P düzeyleri arasında istatistiki açıdan fark p

Anahtar Kelimeler:

alkalin fosfotaz, buzağı, inek, mineral metabolizma bozukluğu, fosfor, doğum sonrası dönem, kalsiyum, hipokalsemi, doğum felci, biyokimyasal parametreler

İnvestigation on the relationship between postpartal hypocalcemic cows and their calves with regard to calcium phosphorus and alkaline phosphatase

In the present study, calcium, inorganic phosphorus and alkaline phosphatase concentrations in serum samples obtained from postpartal normal and postpartal hypocalcemic dairy cows and their neonatal calves were aimed to determine. For this purpose 30 dairy cows ( 10 healthy control group and 20 hypocalcemic group) which belong to different breeds (Holstein, Simental, Sweedish Grey, Jersey and their cross breeds) and their calves were used. The animals used were from the region of Elazig. For the treatment of all hypocalcemic dairy cows; calcium (Vetacalsin® Richter Pharma-Austria), phosphorus (Fosfocure Forte® Provet- Turkey), Vit AD3EC (Richtasol® Richter Pharma-Austria) were used intravenously. Ten ml of blood samples were taken from v.jugularis before the treatment and 1 hour after treatment from hypocalcemic cows, from calves before treatment of hypocalcemic cows and from control group cows and their calves 1 and 48 hours after parturition to determine Ca, P and ALP concentrations. The average Ca, P and ALP values of hypocalcemic cows before treatment were 4.88±020 mg/dl, 2.40±0.25 mg/dl and 56.46±2.20 U/L respectively. The same values for control group cows were 8.65±033 mg/dl, 4.71±029 mg/dl and 48.30±2.41 U/L respectively. When these values compared with regard to hypocalcemic and control animals Ca, P (p<0.001) and ALP (p<0.05) values were different significantly. The average Ca, P and ALP serum values of hypocalcemic cows after treatment were 9.29±0.20 mg/dl, 5.36±0.24 mg/dl and 62.90±2.26 U/L respectively. When these values compared with regard to before treatment and after treatment Ca (p<0.001), P and ALP (p<0.01) values were different significantly. When the average Ca, P and ALP serum values of hypocalcemic cows after treatment and the control group animals compared, statistical differences were not significant. When the average Ca, P and ALP serum values of the calves of hypocalcemic animals and the control group calves compared, statistical difference wasn’t observed. As a result, while the serum Ca, P and ALP values of hypocalcemic cows had significant differences compared to the values obtained from control animals, the same values obtained from calves of hypocalcemic and of control animals were not different significantly. Therefore, results obtained from this study suggest that calves of hypocalcemic animals did not affected with regard to Ca, P and ALP values and detailed studies in the future should be performed on this subject.

Keywords:

alkaline phosphatase, calves, cows, mineral metabolism disorders, phosphorus, postpartum period, calcium, hypocalcaemia, parturient paresis, biochemical parameters,

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