Ahmet Selçuk DİNDAR, SACİT NURİ GÖRGEL, Mustafa Ozan HORSANALI, Fulya Çakalağaoğlu ÜNAY, Kutan ÖZER

Geç dönem metakron testis tümörü: Olgu sunumu

Erkeklerin tüm yaşamları boyunca testis tümörüne yakalanma insidansı % 0.2 düzeyindedir. Testis tümörlerinin %90-95'i germinal dokudan kaynaklanır. Testisin germ hücreli tümörleri pure seminom ve nonseminomatöz germ hücreli tümörler olarak sınıflandırılırlar. Bilateral olma sıklığı % 1-4 oranındadır. Bilateral testis tümörlerinden en sık görülen germ hücreli tümör seminomdur. Ancak en sık rastlanılan bilateral tümör malign lenfomadır. Günümüzde malign ve orijini bilinmeyen testis tümörlerinin tedavisinde radikal orşiektomi standart tedavi olarak düşünülmektedir. Biz burada seminom sonrası metakron olarak karşı testiste ortaya çıkan miks germ hücreli tümör vakasını sunduk.

Long term metachronous testicular tumor: A case report

The incidence of developing testicular cancer is % 0.2 during the entire life span. 90-95% of testiculer tumors stem from germinal tissue. The testicular germ cell tumors are classified as pure seminoma germ cell tumors and nonseminomatous germ cell tumors. The incidence rate of bilateral is 1-4%. Seminoma is the most common germ cell tumor among bilateral testicular cancer. But the most common bilateral tumor is malignant lymphoma. Today radical orchiectomy is considered standart therapy for testiculer tumors. We presented a case with metachronous testiculer tumor whose first pathologic evaluation was reported as seminoma and second one was reported as nonseminomatous germ cell tumor.

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1. Deotra A, Mathur DR, Vyas MC. A 18 years study of tes- ticular tumours in Jodhpur, Western Rajasthan. Postgrad Med J 1994;40:68-70.
2. Akdogan B, Divrik RT, Tombul T, Yazici S, Tasar C, Zor- lu F, ve ark. Bilateral testicular germ cell tumors in Turkey: Increase in incidence in last decade and evaluation of risk factors in 30 patients. J Urol 2007; 178:129-133.
3. Hoei-Hansen CE, Rajpert-De Meyts E, Daugaard G, Skak- kebaek NE. Carcinoma in situ testis, the progenitor of tes- ticular germ cell tumours: a clinical review. Ann Oncol 2005;16: 863-8.
4. Dieckmann KP, Loy V. The value of the biopsy of contrala- teral testis in patients with testicular germ cell cancer:the recent German experience.APMIS 1998 ;106:13-20.
5. Sarıcı H, Telli O, Eroğlu M . Bilateral testicular germ cell tu- mors Turkish Journal of Urology 39: 249-52 • doi:10.5152/ tud.2013.062.
6. Andrew JS, Timothy DG. Neoplasms of the Testis Campbell- Walsh Urology 10th ed. Philadelphia, Saunders Elsevier 2012;837-70.
7. Alan J.Wein, Kavoussi LR, Novick AC, Partin AW, Peters CA. Campbell-Walsh Urology. 9th ed. Philadelphia, Saun- ders Elsevier, 2007;893- 958.
8. Che M, Tamboli P, Ro JY, Park DS, Ro JS, et al. Bilateral testicular germ cell tumors twenty-year experience at M.D. Anderson Cancer Center. Cancer 2002;95:1228-1233.
9. Hentrich M, Weber N, Bergsdorf T et al. Management and outcome of bilateral testicular germ cell tumors: Twenty- five year experience in Munich. Acta Oncol 2005;44: 529- 36.
10. Heidenreich A, Albers P, Krege S. Management of bilate- ral testicular germ cell tumors--experience of the German Testicular Cancer Study Group (GTCSG). Eur Urol Suppl 2006; 5: 97.
11. Livsey JE, Taylor B, Mobarek N, Cooper RA, Carrington B, Logue PJ. Patterns of relapse following radiotherapy for sta- ge I seminoma of the testis: implications for followup. Clin Oncol R Coll Radiol 2001;13:296-300.