Bu çal›flmada Tilapia zilli'de ortam›n farkl› kurflun deriflimlerinin ve etkide kalma süresinin çeflitli dokulardaki kurflun birikimine etkileri incelenmifltir. Deney materyali 1, 7, 15 ve 30 günlük süreler ile 1.0, 2.5 ve 5.0 ppm kurflun deriflimlerinin etkisinde tutularak solungaç, karaci¤er, böbrek ve beyin dokular›ndaki kurflun birikim düzeyleri atomik absorbsiyon spektrofotometresi (AAS) kullan›larak saptanm›flt›r. Genel olarak ortam deriflimine ve etkide kalma süresine ba¤l› olarak dokulardaki kurflun birikiminde art›fl görülmüfltür. ‹ncelenen dokularda biriken toplam kurflunun solungaç, karaci¤er, böbrek ve beyin dokular›ndaki da¤›l›m› s›ras›yla %15.47, %6.10, %52.87 ve %25.56 olarak belirlenmifltir (Böbrek > Beyin > Solungaç > Karaci¤er). Böbrek dokusunda kurflun birikim düzeyinin yüksek olmas›, bu dokunun kurflun ba¤lay›c› proteinler içermesi ve metal at›l›m›n›n önemli düzeyde bu doku üzerinden olmas› gibi nedenlerle aç›klanabilir.

In this study, the accumulation of lead in various tissues of Tilapia zilli was tested at varying concentrations of lead in the medium for different exposure times. Experimental animals were exposed to 1.0, 2.5 and 5.0 ppm lead over periods of 1, 7, 15 and 30 days and accumulation of lead in gill, liver, kidney and brain tissues was determined by atomic absorbtion spectrophotometry (AAS). In general, the accumulation of lead in tissues increased with increasing concentrations of lead in the experimental medium and with increasing time of experiment. The ratios of total lead in the tissues were 15.47, 6.10, 52.87 and 25.56% in the gill, liver, kidney and brain respectively (Kidney > Brain > Gill > Liver). The high level of lead accumulation in the kidney tissue may be explained by the fact that this tissue contains lead combaining proteins, and a high level of metal is disposed of with the aid of kidney tissue.