Bay Aysun KARABULUT, Eser KILIÇ, Özlem Makbule AYCAN, Metin ATAMBAY, Nilgün DALDAL, Süleyman YAZAR, Sönmez Gülden TAMER

The Effect of Dust-Mites on Nitric Oxide Production

Aim: We aimed to investigate the effect of house dust mite on the level of nitric oxide in patients who had dust mite in their houses and suffering from rhinitis and/or asthma and/or eczema-like allergic symptoms and were positive for skin tests (Prick). Materials and Methods: The effect of dust-mites on nitric oxide concentration was investigated using Griess method in patients who had allergic symptoms and were positive for skin tests. Results: The plasma nitric oxide level was found to be statistically higher in patients who had dust mite in their houses and suffering from allergic symptoms and were positive for skin tests than in patients who did not have dust mite in their houses but were positive for skin tests or negative for skin tests. In addition, there was no statistical difference in the level of nitric oxide between the patients who did not have dust mite in their houses but were positive for skin tests and the patients who did not have dust mite in their houses and were negative for skin tests. Conclusions: There seems to be an effect of house dust mite on the level of nitric oxide. However, the molecular mechanism underneath of this effect is not yet clear. A plausible explanation for this might be the intrinsic radical properties of nitric oxide and its protective effect against the parasitic agents.

Anahtar Kelimeler:

Dust-mite, nitric oxide

The Effect of Dust-Mites on Nitric Oxide Production

Keywords:

Dust-mite, nitric oxide,

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