To determine the influence of circulatory factors on recovery from neuromuscular block, we measured train of four (TOF) response in the arm with tourniquet inflated during TOF = 0.1 and compared this with data from a control arm in 40 patients under fentanyl-propofol-nitrous oxide-isoflurane anaesthesia. Patients were allocated randomly to receive either atracurium 0.5 mg/kg (n=20) or vecuronium 0.1 mg/kg (n=20). The TOF response of ulnar nerve in both arms was recorded in every 12 sec. When neuromuscular block was 90% (TOF = 0.1), the tourniquet was inflated to a pressure of 300 mmHg, and when a neuromuscular block recovery of 75% was reached, the block recovery time in both perfused and tourniquet arms was determined. The recorvery from neuromuscular block was markedly delayed in the tourniquet arms in both groups (p

To determine the influence of circulatory factors on recovery from neuromuscular block, we measured train of four (TOF) response in the arm with tourniquet inflated during TOF = 0.1 and compared this with data from a control arm in 40 patients under fentanyl-propofol-nitrous oxide-isoflurane anaesthesia. Patients were allocated randomly to receive either atracurium 0.5 mg/kg (n=20) or vecuronium 0.1 mg/kg (n=20). The TOF response of ulnar nerve in both arms was recorded in every 12 sec. When neuromuscular block was 90% (TOF = 0.1), the tourniquet was inflated to a pressure of 300 mmHg, and when a neuromuscular block recovery of 75% was reached, the block recovery time in both perfused and tourniquet arms was determined. The recorvery from neuromuscular block was markedly delayed in the tourniquet arms in both groups (p