Cihangir ÖZASLAN, Can ATALAY, Işın PAK, Kerim Bora YILMAZ

Histopathological and Clinical Characteristics of Secretory Carcinoma of the Breast

Secretory breast carcinoma is a rare form of invasive breast carcinoma constituting less than 1% of all breast cancer cases. Since insufficient data have been compiled about this rare tumor, it is important to report every case of secretory breast carcinoma in an effort to better understand the histopathological and clinical characteristics of this tumor and to contemplate the most appropriate therapeutic approach. In this report, two adult female patients over 50 years of age and a 14-year-old girl were reviewed with a detailed immunohistochemical work-up to define the clinical and molecular characteristics of secretory breast carcinoma.

Anahtar Kelimeler:

Secretory breast cancer, triple negative, immunohistochemistry

Histopathological and Clinical Characteristics of Secretory Carcinoma of the Breast

Keywords:

Secretory breast cancer, triple negative, immunohistochemistry,

PDF

___

Tavassoli FA, Norris HJ. Secretory carcinoma of the breast. Cancer 1980; 45: 2404-13.
Karl SR, Ballantine TV, Zaino R. Juvenile secretory carcinoma of the breast. J Pediatr Surg 1985; 20: 368-71.
Bond SJ, Buchino JJ, Nagaraj HS, McMasters KM. Sentinel lymph node biopsy in juvenile secretory carcinoma. J Pediatr Surg 2004; 39: 120-1.
Richard G, Hawk JC III, Baker AS Jr, Austin RM. Multicentric adult secretory breast carcinoma: DNA flow cytometric findings, prognostic features, and review of the world literature. J Surg Oncol 1990; 44: 238-44.
Ozaslan C, Kuru B. Lymphedema after treatment of breast cancer. Am J Surg 2004; 187: 69-72.
Vieni S, Cabibi D, Cipolla C, Fricano S, Graceffa G, Latteri MA. Secretory breast carcinoma with metastatic sentinel lymph node. World J Surg Oncol 2006; 4: 88.
Krausz T, Jenkins D, Grontoft O, Pollock DJ, Azzopardi JG. Secretory carcinoma of the breast in adults: emphasis on late recurrence and metastasis. Histopathology 1989; 14: 25-36.
Lamovec J, Bracko M. Secretory carcinoma of the breast: light microscopical, immunohistochemical flow cytometric study. Mod Pathol 1994; 7: 475-9.
Arce C, Cortes-Padilla D, Huntsman DG, Miller MA, Duennas- Gonzales A, Alvarado A et al. Secretory breast carcinoma of the breast containing the ETV6-NTRK3 fusion gene in a male: case report and review of the literature. World J Surg Oncol 2005; 3: 35.
Grabellus F, Worm K, Willruth A, Schmitz KJ, Otterbach F, Baba HA et al. ETV6-NTRK3 gene fusion in a secretory carcinoma of the breast of a male-to-female transsexual. Breast 2005; 14: 71-4.