Evaluation of malaria cases in individuals after traveling to endemic regions of the world

This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning with chills. Three patients had prophylaxis with doxycycline, but all stopped the prophylaxis early of their own volition. P. falciparum was the parasitic agent in all cases. A regimen of artemisinin and lumefantrine was administered in 18 of the 25 cases; quinine plus doxycycline was given in 3, and chloroquine was administered in the remaining 4. Usage of these regimens cured all cases of malaria without complications. Conclusion: The importance of prophylaxis of malaria was demonstrated. Malaria should also be included in the differential diagnosis of patients with fever that have a history of travel to endemic regions.

Evaluation of malaria cases in individuals after traveling to endemic regions of the world

This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning with chills. Three patients had prophylaxis with doxycycline, but all stopped the prophylaxis early of their own volition. P. falciparum was the parasitic agent in all cases. A regimen of artemisinin and lumefantrine was administered in 18 of the 25 cases; quinine plus doxycycline was given in 3, and chloroquine was administered in the remaining 4. Usage of these regimens cured all cases of malaria without complications. Conclusion: The importance of prophylaxis of malaria was demonstrated. Malaria should also be included in the differential diagnosis of patients with fever that have a history of travel to endemic regions.

___

  • Özbilgin A, Topluoglu S, Es S, Islek E, Mollahaliloglu S, Erkoc Y. Malaria in Turkey Successful control and strategies for achieving elimination. Acta Tropica 2011; 120: 15–23.
  • WHO. World Malaria Report: 2011. Geneva: World Health Organization; 2011.
  • Özbilgin A, Tamay AT. Sıtma tanısında yenilikler. ANKEM Derg 2000; 14: 260–5 (article in Turkish).
  • Mert A, Tabak F, Özaras R, Öztürk R, Aktuğu Y. Malaria: a review of 33 cases. Flora 2001; 6: 118–25 (article in Turkish with an abstract in English).
  • İnan A, Erdem İ, Engin OD, Hitit G, Ceran N, Senbayrak S, Özyürek SÇ, Karagül E, Göktaş P. Malaria: an evaluation of 40 cases. Türkiye Parazitol Derg 2010; 34: 147–51 (article in Turkish with an abstract in English).
  • Ser O, Çetin. Antalya ilinde 2001 ile 2011 yılları arasındaki sıtma vakalarının değerlendirilmesi. Türkiye Parazitol Derg 2012; 36: 4–8 (article in Turkish).
  • Mandell GI, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 6th ed. Philadelphia, PA, USA: Elsevier; 2005. pp. 3121–38.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Attachment style and perceived social support as predictors of biopsychosocial adjustment to cancer

Ayşe Gül YILMAZ ÖZPOLAT, Tuğba AYAZ, Özlem KONAĞ, Asiye ÖZKAN

Comparison of the effects of different percutaneous tracheotomy techniques on acute tracheal trauma

Cengiz Bekir DEMİREL, Hacer HALTAŞ, Hasan Kutluk PAMPAL, Yusuf ÜNAL, Berrin IŞIK, Mükerrem UYSAL

An investigation of pulmonary findings of Crimean Congo haemorrhagic fever patients

Sami KINIKLI, Ali Pekcan DEMİRÖZ, Gülden BİLGİN, Şerife ALTUN, Çiğdem HATİPOGLU ATAMAN, Cemal BULUT

Liver enzymes, mean platelet volume, and red cell distribution width in gestational diabetes

Serpil ERDOĞAN, Özhan ÖZDEMİR, Halef Okan DOĞAN, Sevilay SEZER, Cemal Reşat ATALAY, Fatma Meriç YILMAZ, Yüksel KOCA

Factors associated with the Pain Catastrophizing Scale and validation in a sample of the Turkish population

Mustafa SÜREN, İsmail OKAN, Aziz Mehmet GÖKBAKAN, Ziya KAYA, Ünal ERKORKMAZ, Semih ARICI, Serkan KARAMAN, Mürsel KAHVECİ

The obesity prevalence among students between the ages of 5 and 19 in Kütahya

Mustafa BİRİNCİ, Kamil TÜRKMEN, Aylin SAYAN, Mevlüt YILDIZ, Mehmet KAYA

Epistaxis in geriatric patients

Alper YÜKSEL, Hanifi KURTARAN, Ekrem Said KANKILIÇ, Nebil ARK, Kadriye Şerife UĞUR, Mehmet GÜNDÜZ

Ocular surface culture changes in patients after septoplasty

Mahmut ÖZKIRIŞ, Zeliha KAPUSUZ GENCER, Çiğdem KADER, Levent SAYDAM

Evaluation of outer hair cell function and medial olivocochlear efferent system in patients with type II diabetes mellitus

Hayriye KARABULUT, İsmail KARABULUT, Muharrem DAĞLI, Yıldırım Ahmet BAYAZIT, Şule BİLEN, Yusuf AYDIN, Serdar GÜLER, İsmet BAYRAMOĞLU

Choroidal thickness in healthy Turkish subjects

Erol COŞKUN, Seydi OKUMUŞ, Bülent GÜRLER, Ramazan YAYUSPAYI, Burak ÖREN, Erdal KAYDU, Ayşegül ÇÖMEZ, İbrahim ERBAĞCI