A rare presentation of brucellosis: polyradiculopathy and peripheral neuritis

To present 8 patients with polyradiculopathy or polyradiculoneuritis caused by brucellosis. Polyradiculopathy or polyradiculoneuritis are occasional neurological involvements of brucellosis. Materials and methods: The diagnosis was made with clinical, serological and/or cerebrospinal fluid, and electromyographic examinations. Results: All of the patients except one improved quickly after specific antimicrobial treatment. Furthermore, electrophysiological examinations revealed normal findings in 6 patients. Conclusion: This clinical form of brucellosis is mostly reversible if it is diagnosed earlier and treated effectively.

A rare presentation of brucellosis: polyradiculopathy and peripheral neuritis

To present 8 patients with polyradiculopathy or polyradiculoneuritis caused by brucellosis. Polyradiculopathy or polyradiculoneuritis are occasional neurological involvements of brucellosis. Materials and methods: The diagnosis was made with clinical, serological and/or cerebrospinal fluid, and electromyographic examinations. Results: All of the patients except one improved quickly after specific antimicrobial treatment. Furthermore, electrophysiological examinations revealed normal findings in 6 patients. Conclusion: This clinical form of brucellosis is mostly reversible if it is diagnosed earlier and treated effectively.

___

  • Young EJ. Brucella species. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 6th ed. Philadelphia (PA): Churchill Livingstone; 2005. p.2669-74. 2. Shakir RA. Neurobrucellosis. Postgrad Med J 1986; 62: 1077-9.
  • Coskun O, Ertem TG, Ergun U, Kutlu G, Tulek N, Inan LE. Evaluation of brainstem auditory potential in brucellosis patients with and without neurological involvement. Intern J Neuroscience 2005; 15: 717-23. 4. Omar FZ, Zuberi S, Minns RA. Neurobrucellosis in childhood: six new cases and a review of the literature. Dev Med Child Neurol 1997; 39: 762-5.
  • Gul HC, Erdem H, Bek S. Overview of neurobrucellosis: a pooled analysis of 187 cases. Int J Infect Dis 2009; 13: e339-43.
  • Oh SJ. Clinical electromyography: Nerve conduction studies. 2nd ed. Baltimore: Williams & Wilkins; 1993.
  • Kochar DK, Agarwal N, Jain N, Sharma BV, Rastogi A, Meena CB. Clinical profi le of neurobrucellosis—a report on 12 cases from Bikaner (north-west India). J Assoc Physicians India 2000; 48: 376-80.
  • Vajramani GV, Nagmoti MB, Patil CS. Neurobrucellosis presenting as an intra-medullary spinal cord abscess. Ann Clin Microbiol Antimicrob 2005; 4: 14. 9. Al Deeb SM, Yaqub BA, Sharif HS, Phadge JG. Neurobrucellosis: clinical characteristics, diagnosis, and outcome. Neurology 1989; 39: 498-501.
  • Shakir RA, Al Din ASN, Araj GF, Lulu AR, Mousa AR, Saadah MA. Clinical categories of neurobrucellosis: a case report on 19 cases. Brain 1987; 110: 213-23.
  • Goktepe AS, Alaca R, Mohur H, Coskun U. Neurobrucellosis and a demonstration of its involvement in spinal roots via magnetic resonance imaging. Spinal Cord 2003; 41: 574-6.
  • Özerbil ÖM, Ural O, Topatan Hİ, Erongun U. Lumbar spinal root compression caused by Brucella granuloma. Spine 1998; 23: 491-3.
  • Bahemuka M, Shemena AR, Panayiotopoulos CP, Al-Aska AK, Obeid T, Daif AK. Neurological syndromes of brucellosis. J Neurol Neurosurg Psychiatry 1988; 51: 1017-21.
  • Hesseling AC, Marais BJ, Cotton MF. A child with neurobrucellosis. Ann Trop Paediatr 2003; 23: 145-8.
  • Pascual J, Combarros O, Polo JM, Berciano J. Localized CNS brucellosis: report of 7 cases. Acta Neurol Scand 1988; 78: 282- 9.
  • Bashir R, Al-Kawi MZ, Harder EJ. Nervous system brucellosis: diagnosis and treatment. Neurology 1985; 35: 1576-81.
  • Reitman CA, Watters WC. Spinal brucellosis: case report in the United States. Spine 2002; 27: E250-2.
  • Yetkin MA, Bulut C, Erdinc FS, Oral B, Tulek N. Evaluation of the clinical presentations in neurobrucellosis. Int J Infect Dis 2006; 10: 446-52.
  • Demiraslan H, Metan G, Meşe EA, Yildiz O, Aygen B, Sumerkan B et al. Neurobrucellosis: an evaluation of a rare presentation of brucellosis from a tertiary care centre in Central Anatolia, Turkey. Trop Doct 2009; 39: 233-5.
  • Ranjbar M, Rezaiee AA, Hashemi SH, Mehdipour S. Neurobrucellosis: report of a rare disease in 20 Iranian patients referred to a tertiary hospital. East Mediterr Health J 2009; 15: 143-8.
  • Gul HC, Erdem H, Gorenek L, Ozdag MF, Kalpakci Y, Avci IY et al. Management of neurobrucellosis: an assessment of 11 cases. Intern Med 2008; 47: 995-1001.
  • Kutlu G, Ertem GT, Coskun O, Ergun U, Gomceli YB, Tulek N et al. Brucella: A cause of peripheral neuropathy. Eur Neurol 2009; 61: 33-8.
  • Mousa AM, Araj GF, Koshy TS, Muhtaseb SA, Al-Mudallal DS. Neurological complications of brucella spondylitis. Acta Neurol Scand 1990; 81: 16-23.
  • Ulas UH, Hamamcioglu K, Eroglu E, Odabasi Z, Alanoglu E, Demirkaya S et al. Paraplegia associated with brucellosis involving the anterior lumbrosacral nerve roots. J Peripher Nerv Syst 2003; 8: 8-12.
  • Bucher A, Gaustad P, Pape E . Chronic neurobrucellosis due to Brucella melitensis. Scand J Infect Dis 1990; 22: 223-6.
  • Tanyel E, Coban AY, Koruk ST, Simsek H, Hepsert S, Cirit OS. Actual antibiotic resistance pattern of Brucella melitensis in central Anatolia. An update from an endemic region. Saudi Med J 2007; 28: 1239-42.
  • Baykam N, Esener H, Ergönül Ö, Eren Ş, Çelikbas A, Dokuzoğuz B. In vitro antimicrobial susceptibility of Brucella species. Int J Antimicrob Agents 2004; 23: 405-7.
  • Bodur H, Erbay A, Akinci E, Colpan A, Cevik MA, Balaban N. Neurobrucellosis in an endemic area of brucellosis. Scand J Infect Dis 2002; 35: 94-7.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Hipotansiyon insidansı üzerine etkiler: sezaryen için spinal anestezide hiperbarik, isobarik bupivakain ve kombinasyonları

Işıl TURAN ÖZKOÇAK, İnan İlker ARIKAN, Hilal AYOĞLU, Bülent Serhan YURTLU, Rahşan Dilek OKYAY, Gülay KAYHAN ERDOĞAN, Volkan HANCI, Sedat HAKİMOĞLU, Ülkü BAYAR, Selime Evrim BOSTANKOLU

The evaluation of the results of adjuvant chemoradiotherapy in patients with gastric cancer: results from a single center in eastern Anatolia

Mehmet BİLİCİ, Hilal ÖZMEN KIZILTUNÇ, Mustafa KANDAZ, Salim Başol TEKİN, Kerim ÇAYIR, Mustafa Vecdi ERTEKİN

Artificial urinary sphincter implantation: what do patients and urologists face?

Raşit ALTINTAŞ, Mehmet Ceyhun ÖZYURT, Adnan ŞİMŞİR

Mean platelet volume as a marker of future cardiovascular disease risk in pregnant women with impaired fasting glucose and impaired glucose tolerance

Nermin KÖŞÜŞ, Aydın KÖŞÜŞ, Nilgün TURHAN

Therapeutic effects of Mycobacterium phlei cell wall extracts

Mehmet Selçuk KESKİN, Esra BÜBER, Ömür ÇELİKBIÇAK, Bağnu ORHAN, Abdurrahim Haluk ÖZEN, Naciye Leyla AÇAN, Zeynep SARIBAŞ, Alpaslan ALP, Bekir SALİH

Ovariectomy decreases biomechanical quality of skin via oxidative stress in rat

Mehmet BERKÖZ, Ebru BALLI, Serap YALIN, Ülkü ÇÖMELEKOĞLU

Prognostic impact of matrix metalloproteinases (MMP-9 and MMP-2) and vascular endothelial growth factor expression in non-small cell lung cancer

Leyla MEMİŞ, Nalan AKYÜREK, Jale KARAKAYA, Şenay YILMAZ, Ahmet YURDAKUL, Can ÖZTÜRK

The effect of soya bean meal on tibial articular cartilage growth in mice after suckling period: a histomorphometric and biochemical study

Zahra TOOTIAN, Simin FAZELIPOUR, Seyed Babak KIAEI, Amir Hossein EGHTESAD

Catechol-O-methyltransferase Val108/158Met gene and alcoholism in Turkish subjects

Burçin TEZCANLI, Buket KOSOVA, Bülent KAYAHAN, Hakan COŞKUNOL, Ayşe Ender ALTINTOPRAK

Crataegus orientalis yapraklarının etanol ekstresinin antinosiseptif, anti-infl amatuvar ve antioksidan etkileri

Zeynep BOR, Rana ARSLAN, Nurcan BEKTAŞ, Sevda PIRILDAR, Ali Aslan DÖNMEZ