LINJIONG ZHANG, MINGYAN YANG, Beizhen HU, ZHAOHUI SUN, XINGHAI LIU, JIANQUAN WENG, CHENGXIA TAN

3726

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-$a$]pyridine derivatives

A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

Anahtar Kelimeler:

1, 2, 4-Triazolo[4, 3-$a$]pyridine, urea, microwave-assisted synthesis

Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-a]pyridine derivatives

A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.

Keywords:

1, 2, 4-Triazolo[4, 3-$a$]pyridine, urea, microwave-assisted synthesis,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: Yılda 6 Sayı
Yayıncı: TÜBİTAK

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