The Assessment of Quality of Life, Depression and Anxiety in Siblings of Children with Cancer: A Case-Control Study

The Assessment of Quality of Life, Depression and Anxiety in Siblings of Children with Cancer: A Case-Control Study

OBJECTIVE Pediatric cancers may have traumatic, adverse effects on healthy siblings of children with cancer. The majority of studies on the subject have been performed in Western societies, and few controlled studies implementing validated surveys have been performed. The aim of this study is to investigate the quality of life, prevalence of anxiety and depression and associated factors in healthy siblings of children with cancer. METHODS Sixty children aged 8-16 years-old with siblings with cancer were included as the case group and sixty children with siblings without cancer were enrolled as the control group. The Revised Child Anxiety and Depression Scale (RCAD-S) and the Questionnaire for Quality of Life Assessment for Children and Adolescents Parent Form (Kid-KINDL) were used to evaluate anxiety/depression symptoms and quality of life respectively. RESULTS The case group consisted of 30 boys and 30 girls (12.08±2.61 years), and the control group of 31 boys and 29 girls (11.40±2.11 years). Depression/anxiety symptoms were significantly higher in the case group than in the control group (p

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  • 1. Fitzmaurice C, Dicker D, Pain A, Hamavid H, MoradiLakeh M, MacIntyre MF, et al. The global burden of cancer. JAMA oncol 2013;1(4):505–27. 2. Bhakta N, Force LM, Allemani C, Atun R, Bray F, Coleman MP, et al. Childhood cancer burden: a review of global estimates. Lancet Oncol 2019;20(1):e42–e53. 3. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68(6):394–424. 4. Long KA, Lehmann V, Gerhardt CA, Carpenter AL, Marsland AL, Alderfer MA. Psychosocial functioning and risk factors among siblings of children with cancer: An updated systematic review. Psychooncology 2018;27(6):1467–79. 5. Walczak A, McDonald F, Patterson P, Dobinson K, Allison K. How does parental cancer affect adolescent and young adult offspring? A systematic review. Int J Nurs Stud 2018;77:54–80. 6. Long KA, Marsland AL, Wright A, Hinds P. Creating a tenuous balance: Siblings’ experience of a brother’s or sister’s childhood cancer diagnosis. J Pediatr Oncol Nurs 2015;32(1):21–31. 7. Donnan BM, Webster T, Wakefield CE. What about school? Educational challenges for children and adolescents with cancer. Aust Educ Dev Psychol 2015;32(1):23–40. 8. Samson K, Rourke MT, Alderfer MA. A qualitative analysis of the impact of childhood cancer on the lives of siblings at school, in extracurricular activities, and with friends. Clin Pract Pediatr Psychol 2016;4(4):362–72. 9. Williams PD, Ridder EL, Setter RK, Liebergen, A, Curry H, Piamjariyakul U, et al. Pediatric chronic illness (cancer, cystic fibrosis) effects on well siblings: Parents’ voices. Issues Compr Pediatr Nurs 2009;32(2):94–113. 10.Björk M, Wiebe T, Hallström I. An everyday struggle - Swedish families’ lived experiences during a child’s cancer treatment. J Pediatr Nurs 2009;24(5):423–32. 11.Khoury MN, Huijer HA, Doumit MAA. Lebanese parents’ experiences with a child with cancer. Eur J Oncol Nurs 2013;17(1):16–21. 12.Prchal A, Landolt MA. How siblings of pediatric cancer patients experience the first time after diagnosis: A qualitative study. Cancer Nurs 2012;35(2):133–40. 13.Cordaro G, Veneroni L, Massimino M, Clerici CA. Assessing psychological adjustment in siblings of children with cancer: Parents’ perspectives. Cancer Nurs 2012;35(1):E42–50. 14.Santacroce SJ, Crandell JB. Feasibility and preliminary findings from a pilot study of allostatic load in adolescent-young adult childhood cancer survivors and their siblings. J Pediatr Oncol Nurs 2014;31(3):122–34. 15.Huang YL, Yates P, Prior D. Factors influencing oncology nurses’ approaches to accommodating cultural needs in palliative care. J Clin Nurs 2009;18(24):3421– 29. 16.Ay MA, Akyar I. Psychosocial Status of Turkish Families of Pediatric Cancer Patients. J Transcult Nurs 2020;31(3):227–41. 17.Houtzager BA, Grootenhuis MA, Caron HN, Last BF. Quality of life and psychological adaptation in siblings of paediatric cancer patients, 2 years after diagnosis. Psychooncology 2004;138:499–511. 18.Turkish Presidential Official Gazette. Minimum wage determination commission decision. Available at: https://www.resmigazete.gov.tr/eskiler/2017/12/20171230-10.pdf. Accessed Dec 29, 2017. 19.Chorpita BF, Yim L, Moffitt C, Umemoto LA, Umemoto LA, Francis SE. Assessment of symptoms of DSMIV anxiety and depression in children: A revised child anxiety and depression scale. Behav Res Ther 2000;38(8):835–55. 20.Gormez V, Kilincaslan A, Ebesutani C, Orengul AC, Kaya I, Ceri V, et al. Psychometric properties of the parent version of the Revised Child Anxiety and Depression Scale in a clinical sample of Turkish children and adolescents. Child Psychiatry Hum Dev 2017;48(6):922–33. 21.Ravens-Sieberer U, Bullinger M. Assessing healthrelated quality of life in chronically ill children with the German KINDL: first psychometric and content analytical results. Qual Life Res 1998;7(5):399–407. 22.Eser E, Yüksel H, Baydur H, Erhart M, Saatli G, Özyurt BC, et al. The Psychometric Properties of the New Turkish Generic Health-Related Quality of Life Questionnaire for Children (Kid-KINDL). Turk Psikiyatri Derg 2008;19(4):409–17. 23.Serra-Sutton V, Ferrer M, Rajmil L, Tebé C, Simeoni MC, Ravens-Sieberer U. Population norms and cutoff-points for suboptimal health related quality of life in two generic measures for adolescents: the Spanish VSP-A and KINDL-R. Health Qual Life Outcomes 2009;7(1):1–9. 24.Hauken MA, Senneseth M, Dyregrov A, Dyregrov K. Anxiety and the quality of life of children living with parental cancer. Cancer nurs 2018;41(1):E19–E27. 25.Kazak AE, Hocking MC, Ittenbach RF, Meadows AT, Hobbie W, DeRosa BW, et al. A revision of the intensity of treatment rating scale: classifying the intensity of pediatric cancer treatment. Pediatr Blood Cancer 2012;59(1):96–9. 26.Patterson P, Millar B, Visser A. The development of an instrument to assess the unmet needs of young people who have a sibling with cancer: Piloting the sibling cancer needs instrument (SCNI). J Pediatr Oncol Nurs 2011;28(1):16–26. 27.Alderfer MA, Hodges JA. Supporting siblings of children with cancer: A need for family–school partnerships. School Mental Health 2010;2(2):72–81. 28.Long KA, Alderfer MA, Ewing LJ, Marsland AL. The role of contextual threat in predicting self-reported distress among siblings of children with cancer. J Clin Psychol Med Settings 2013;20(2):199–208. 29.Long KA, Marsland AL, Alderfer MA. Cumulative Karayağmurlu et al. 25 The Assessment of Quality of Life, Depression and Anxiety in Siblings of Children with Cancer family risk predicts sibling adjustment to childhood cancer. Cancer 2013;119(13):2503–10. 30.Dolgin MJ, Blumensohn R, Mulhern RK, Orbach J, Sahler OJ, Roghmann KJ, et al. Sibling adaptation to childhood cancer collaborative study: Cross-cultural aspects. J Psychosocial Oncol 1997;15(1):1–14. 31.Yeh LC, Kellet U, Henderson S, Chen KH. How does culture shape roles and relationships in Taiwanese family caregiving for an adolescent with cancer? Cancer Nurs 2015;38(3):E35–E41. 32.Barrera M, Fleming CF, Khan FS. The role of emotional social support in the psychological adjustment of siblings of children with cancer. Child Care Health Dev 2004;30(2):103–11. 33.Houtzager BA, Grootenhuis MA, Hoekstra‐Weebers JEHM, Last BF. One month after diagnosis: quality of life, coping and previous functioning in siblings of children with cancer. Child Care Health Dev 2005;31(1):75–87. 34.Bansal M, Sharma KK, Vatsa M, Bakhshi S. Comparison of health-related quality of life of children during maintenance therapy with acute lymphoblastic leukemia versus siblings and healthy children in India. Leuk Lymphoma 2013;54(5):1036–41. 35.Bansal M, Sharma KK, Bakhshi S, Vatsa M. Perception of Indian parents on health-related quality of life of children during maintenance therapy of acute lymphoblastic leukemia: A comparison with siblings and healthy children. J Pediatr Hematol Oncol 2014;36(1):30–6. 36.Dinleyici M, Çarman KB, Özdemir C, Harmancı K, Eren M, Kirel B, et al. Quality-of-life Evaluation of Healthy Siblings of Children with Chronic Illness. Balkan Med J 2020;37(1):34–42. 37.McDonald FEJ, Patterson P, White KJ, Butow P, Bell ML. Predictors of unmet needs and psychological distress in adolescent and young adult siblings of people diagnosed with cancer. Psychooncology 2015;243(3):333–40. 38.Stiffler D, Haase J, Hosei B, Barada B. Parenting experiences with adolescent daughters when mothers have breast cancer. Oncol Nurs Forum 2008;35(1):113–20. 39.Houtzager BA, Oort FJ, Hoekstra-Weebers JE, Caron HN, Grootenhuis MA, Last, B. F. Coping and family functioning predict longitudinal psychological adaptation of siblings of childhood cancer patients. J Pediatr Psychol 2004;29(8):591–605.
Türk Onkoloji Dergisi-Cover
  • ISSN: 1300-7467
  • Başlangıç: 2015
  • Yayıncı: Ali Cangül
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