Mucinous Breast Carcinoma: A Single-Center Experience
Mucinous Breast Carcinoma: A Single-Center Experience
OBJECTIVETo analyze the clinical and histopathological characteristics and treatment outcomes of patients treatedand followed up for mucinous breast cancer (MBC).METHODSWe retrospectively analyzed the clinical and histopathological characteristics and treatment outcomes of22 patients who were diagnosed with and treated for MBC at our center between 2004 and 2016.RESULTSThe mean age was 50 (range: 26–68) years. Ten (47.6%) patients were premenopausal. The tumor was inthe right side in 11 patients (50%), and 64% of the patients had early-stage disease. There were six patientswith the mixed subtype and 16 with the pure subtype. Except for the two patients with metastatic disease,all patients underwent surgery. Axillary lymph node involvement was detected in seven (36%) patients,and the proportion of patients with the pure subtype was 18%. The average duration of follow-up was 59months, during which, four patients had recurrent disease. At 5 years, 81% of the patients were alive. The5-year overall survival rate with pure MBC was 93%.CONCLUSIONMBC is a rare condition and carries a good prognosis. Pure MBC has low axillary lymph node metastasisand a higher survival rate.
___
- 1. TC Sağlık Bakanlığı. Sağlık İstatistikleri Yıllığı 2010. Available at: https://sbu.saglik.gov.tr/Ekutuphane/Yayin/444. Accessed May 28, 2018.
- 2. Tavassoli FA, Devilee P. World Health Organization Classification of Tumors. Tumors of the Breast and Female Genital Organs. 2nd edition. Lyon, F: IARC Press; 2003.
- 3. André S, Cunha F, Bernardo M, Meneses e Sousa J, Cortez F, Soares J. Mucinous carcinoma of the breast: a pathologic study of 82 cases. J Surg Oncol 1995;58(3):162–7.
- 4. Toikkanen S, Kujari H. Pure and mixed mucinous carcinomas of the breast: a clinicopathologic analysis of 61 cases with long-term follow-up. Hum Pathol 1989;20(8):758–64.
- 5. Monzawa S, Yokokawa M, Sakuma T, Takao S, Hirokaga K, Hanioka K, et al. Mucinous carcinoma of the breast: MRI features of pure and mixed forms with histopathologic correlation. AJR Am J Roentgenol 2009;192(3):W125–31.
- 6. Di Saverio S, Gutierrez J, Avisar E. A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma. Breast Cancer Res Treat 2008;111(3):541–7.
- 7. Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, et al. American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol 2010;28(16):2784–95.
- 8. Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007;25(1):118–45.
- 9. Park S, Koo J, Kim JH, Yang WI, Park BW, Lee KS. Clinicopathological characteristics of mucinous carcinoma of the breast in Korea: comparison with invasive ductal carcinoma-not otherwise specified. J Korean Med Sci 2010;25(3):361–8.
- 10.Gündeş E, Aksoy F, Vatansev C, Çakır M. Pure and mixed mucinous carcinoma of the breast. J Breast Health 2013;9:182–5.
- ISSN: 1300-7467
- Başlangıç: 2015
- Yayıncı: Ali Cangül
Sayıdaki Diğer Makaleler
Uğur SELEK, Duygu SEZEN, Yasemin BÖLÜKBAŞI, Yücel SAĞLAM, Vildan ALPAN, Ali İhsan ATASOY, Nülifer KILIÇ DURANKUŞ
Where Should Radiotherapy Stand in the Current era of Rectal Cancer Management?
Uğur SELEK, Duygu SEZEN, Yasemin BÖLÜKBAŞI, Nülifer KILIÇ DURANKUŞ
Musa ALTUN, Kamuran İBİŞ, Canan KÖKSAL, Uğur AKBAŞ
Mucinous Breast Carcinoma: A Single-Center Experience
Nilgün YILDIRIM, Mehmet Naci ALDEMİR
Validity and Reliability of The Turkish Version of Fear of Cancer Recurrence Inventory
Aslı EYRENCİ, Hanife Özlem SERTEL BERK
Prognostic Importance of Ki-67 Labeling Index in Grade II Glial Tumors
Meryem AKTAN, Gül KANYILMAZ, Eray KARAHACIOĞLU, Hatice ÖNDER, Hüseyin BORA, Mehmet KOÇ, Haldun Şükrü ERKAL, Eda YİRMİBEŞOĞLU ERKAL