KOAH infektif alevlenmelerinde atipik patojenlerin rolü
Kronik obstrüktif akciğer hastalığı (KOAH) alevlenmesinin başlıca nedenleri viral ve bakteriyel infeksiyonlardır. Bu çalışmada, KOAH alevlenmelerinde atipik patojenlerin sıklığını saptamak, bu patojenlerin alevlenmenin prognozundaki önemini ve hastanın öyküsü, klinik ve laboratuvar bulgularıyla ilişkilerini belirlemek amaçlanmıştır. Toplam 70 olgunun %32.9’unda tipik, %37.1’inde atipik etkenler belirlenmiştir. Genç ve hava yolu obstrüksiyonu hafif düzeyde olan hastalarda, atipik bakteriyel etkenler daha sık olarak saptanmıştır. Tipik ve atipik etken gruplarında, tedaviye yanıtın farklılık göstermediği saptanmıştır.
Role of atypical pathogens in infectious exacerbations of COPD
Bacterial and viral infections are major causes of chronic obstructive pulmonary disease (COPD) exacerbations This study aimed to find out the frequency of typical and atypical pathogens in the etiology of COPD exacerbations, to evaluate the effect of these infections on the prognosis of the disease and their relationship with the history, clinical and laboratory findings of the patients. Typical agents were determined in 32.9% and atypical agents in in 37.1% of the patients. Atypical pathogens were more commonly isolated from younger patients with mild obstructive disease. There was no change in terms of response to therapy in typical and atypical pneumonia groups.
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