Hayrettin GÖÇMEN, Funda COŞKUN, Balaban Şaduman ADIM, Esra UZASLAN, Oktay GÖZÜ

Sarcoidosis of the breast

Sarkoidoz etyolojisi bilinmeyen ve tüm organları etkileyebilen sistemik bir hastalıktır. Olguların %1'inden azında meme tutulumu bildirilmiştir. Literatürde meme tutulumu ile ilgili 33 civarında olgu yayınlanmıştır. Bildirilen bu olguların 1/3'ünden azında meme, primer tutulum yeridir. Bu nedenle memedeki tutulumlar öncelikle malignite lehine yorumlanmakta ve yapılan cerrahi örnekleme sonucunda tanı konmaktadır. Sarkoidozda meme ve cilt tutulumu birlikteliği ise çok nadirdir. Mediastinoskopi ile sarkoidoz tanısı konmuş 49 yaşında kadın hasta 1999 yılından beri izlenmekteydi. 2002 ve 2004 yıllarında patoloji ile verifiye cilt tutulumu saptanarak iki kez sistemik kortikosteroid tedavisi almıştı. 2006 Mart ayında her iki meme başında büyük nodüler lezyonlar saptanm nodül eksizyonu ve redüksiyon mammoplasti işlemi yapıldı. Histopatoloji sonucu meme sarkoidozu olarak bildirildi. Olgu, meme ve cilt tutulumunun eşlik ettiği akciğer sarkoidozu kabul edildi. Sarkoidozda akciğer, meme ve cilt tutulumunun nadir birlikteliği nedeniyle olgumuzu bildiriyoruz.

Anahtar Kelimeler:

Meme, Kadın, Orta yaşlı, Sarkoidoz

Meme sarkoidozu

Sarcoidosis is a granulomatous disease which might affect many systems. Less than 1% of the cases suffer breast involvement. There are about 33 cases involving breast in the literature. In many cases, systemic symptoms mask breast involvement of sarcoidosis, that was generally recognized in result of surgical operation for malignancy. Breast and skin involvement together is rather rare in sarcoidosis. A 49-yearold female patient with mediastinoscopic diagnosis of sarcoidosis has been followed since 1999. Patient was treated with systemic corticosteroid twice due to skin involvement of sarcoidosis in 2002 and 2004. In 2006 macronodular lesions were found in both of her breast. Nodule excision and reduction mammoplasty were performed with pathological result of noncaseous granulomatous sarcoid inflammation. Patient was admitted as pulmonary sarcoidosis stage II with skin and breast involvement. Since lung, breast and skin involvement together is very rare in sarcoidosis we presented this case.

Keywords:

Breast, Female, Middle Aged, Sarcoidosis,

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