Musculoskeletal pain and quality of life in patients undergoing hemodialysis: a single-center study

Musculoskeletal pain and quality of life in patients undergoing hemodialysis: a single-center study

Objectives: In this study, we aimed to research the frequency of musculoskeletal manifestations of patients receiving hemodialysis treatment, and evaluate the relationship between quality of life and musculoskeletal manifestations of these patients. Methods: Patients undergoing hemodialysis for at least 6 months were included in our study. Patients were asked to complete a questionnaire that formed by the investigators including demographic, clinical features, and musculoskeletal symptoms that frequently seen in patients who receive hemodialysis. Kidney Disease Quality of Life Short Form Version 1.3 (KDQOL-SF 1.3) and Short Form Health Survey (SF 36) questionnaires were completed by the patients and the control group. Blood urea nitrogen, serum creatinine, serum albumin, C-reactive protein (CRP), parathormone (PTH), ferritin, calcium, phosphate, hemoglobin, and Kt/V were measured. Also, the patients were divided into two subgroups according to musculoskeletal symptoms and these subgroups were compared in terms of dialysis adequacy, quality of life scoring and laboratory findings. Results: Seventy-four patients (42 males, 32 females) were enrolled in our study. The mean age of the patients was 60.85 ± 12.29 years. Six-five (87.83%) patients had musculoskeletal symptoms. There was statistically major difference in terms of smoking between subgroups (p = 0.046). We did not detect any correlation between two groups in terms of Kt/V (p = 0.411). Pain in shoulder/neck (41.9%), pain in limbs (58.1%) and pain in back (56.8%) were the most detected musculoskeletal symptoms of the patients. There was statistically significant difference between genders in terms of joint swelling, muscle cramps, pain in limbs, back and neck /shoulder (p = 0.015, p = 0.001, p = 0.008, p = 0.001, and p = 0.004, respectively). We detected that all subunits of KDQOL scores were higher in control group than patients who were included in our study. There was statistically significant relation between emotional role and energy subunits of KDQOL scores and CRP (p = 0.031 and p = 0.025, respectively). Conclusion: The results of our study were not as significant as the results of similar studies, however they are valuable because they show demographic, clinical characteristics, and quality of life of patients receiving hemodialysis in our region.

___

  • 1. Gamondi C, Galli N, Schönholzer C, Marone C, Zwahlen H, Gabutti L, et al. Frequency and severity of pain and symptom distress among patients with chronic kidney disease receiving dialysis. Swiss Med Wkly 2013;143:13750.
  • 2. Bohlke M, Nunes DI, Marini SS, Kitamura C, Andrade M, Von Gysel MP. Predictors of quality of life among patients on dialysis in southern Brazil. Sao Paulo Med J 2008;126:252-6.
  • 3. National Kidney Foundation. Clinical practice guidelines for nutrition in chronic renal failure. KDOQL. Am J Kidney Dis 2000;35:S1-140.
  • 4. Hays RD, Kallich JD, Mapes DL, Coons SJ, Âmin N, Carter WB. Kidney disease quality of life short form (KDQOL-SF) Version 1.3: A Manual for Use Scoring. Washington DC, RAND. 1997.
  • 5. Yildirim A, Ogutmen B, Bektas G, Isci F, Mete M, Tolgay HI. Translation, cultural adaptation, initial reliability and validation of the kidney disease and Quality of Life-Short Form (KDQOL-SF 1.3) in Turkey. Transplant Proc 2007;39:51-4.
  • 6. Ware J, Kosinski M, Keller SD. SF-36 Physical and Mental Health Summary Scales: A User’s Manual. Boston MA, USA: The Health Institute, New England Medical Center, 1994.
  • 7. Hage S, Hage V, El-Khoury N, Azar H, Chelala D, Ziade N. Musculoskeletal disorders in hemodialysis patients: different disease clustering according to age and dialysis vintage. Clinc Rheumot.2019.
  • 8. Khalil G, Mallat S, Topouchian D, Sleilaty G, Roukoz S, Baddoura. [Risk Factors of permanent functional limitations on 210 hemodialysed patients]. J Med Liban 2009;57:237-42. [Article in French]
  • 9. Marzouq MK, Samoudi AF, Samara A, Zyoud SH, Al-Jabi SW. Exploring factors associated with pain in hemodialysis patients: a multicenter cross-sectional study from Palestine. BMC Nephrol 2021;22:96.
  • 10. Kesikburun B, Eksioglu E, Akdag I, Cakcı A. Low back pain in hemodialysis patients: risk factors and its impact on health-related quality of life. Turk J Phys Med Rehab 2018;64:66-71.
  • 11. Linher-Melville K, Shah A, Singh G. Sex differences in neuro(auto)immunity and chronic sciatic nerve pain. Biol Sex Differ 2020;11:62.
  • 12. Caravaco F, Gonzales B, Bayo MA, Luna E. Musculoskeletal pain in patients with chronic kidney disease. Nefrologia 2016;36:433-40.
  • 13. Molsted S, Eidemak I. Musculoskeletal pain reported by mobile patients with chronic kidney disease. Clin Kidney J 2020;13:813-20.
  • 14. Hsu HJ, Yen CH, Hsu KH, Wu IW, Lee CC, Hung MJ, et al. Factors associated with chronic musculoskeletal pain in patients with chronic kidney disease Nephrol 2014;15:6.
  • 15. Generaal E, Vogelzangs N, Macfarlane GJ, Geenen R, Smit JH, Dekker J, et al. Basal inflammation and innate immune response in chronic multisite musculoskeletal pain. Pain 2014;155:1605-12.
  • 16. Gerdle B, Ghafouri B, Ernberg M, Larsson B. Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the micro dialysis technique. J Pain Res 2014;7:313-6.
  • 17. Caravaco F, Gonzales B, Bayo MA, Luna E. Musculoskeletal pain in patients with chronic kidney disease. Nefrologia 2016;36:433-40.
  • 18. Knudsen DP, Eidemak I, Molsted S. Health related quality of life in 2002 and 2015 in patients undergoing hemodialysis: a single center study. Renal Fail 2016;38:1234-9.
  • 19. Türk İ, Ates K, Bıyıklı Z. Quality of life and associated factors in hemodialysis and peritoneal dialysis patients. Cukurova Med J 2020;45:79-88.
  • 20. Ma SJ, Wang WJ, Tang M, Chen H, Ding F. Mental health status and quality of life in patients with end-stage renal disease undergoing maintenance hemodialysis. Ann Palliat Med 2021;10:6112-21.
  • 21. Kuhlmann MK, Kotanko P, Levin NW. Hemodialysis: Dialysis prescription and adequacy. In: Feehally J, Floege J, Tonelli M, Johnson RJ, eds., Comprehensive Clinical Nephrology. 6th. ed., Edinburgh London New York: Elsevier; 2018: pp. 1082-9.
The European Research Journal-Cover
  • ISSN: 2149-3189
  • Yayın Aralığı: 6
  • Başlangıç: 2015
  • Yayıncı: Prusa Medikal Yayıncılık Limited Şirketi
Sayıdaki Diğer Makaleler

Turkish speech-language therapists' perceptions and experiences of augmentative and alternative communication

İbrahim Can YAŞA, Selin TOKALAK

Determining the traditional methods used by newborn women by giving birth: a descriptive study

Aysel BÜLEZ, Mehtap SÖNMEZ, Merva ORHAN, Aygül GÜNEŞ

Does chronic venous insufficiency affect cardiac functions? A speckle tracking echocardiography study

Fatih KOCA, Fatih LEVENT, Ahmet Kağan AS, Fatih KÖKSAL, Ahmet Burak TATLI, Fahriye VATANSEVER, Mehmet DEMİR, Erhan TENEKECİOĞLU

The possible effect of light exposure reduction via eye patches after the examination for retinopathy in premature infants? An observational study in preterm neonates

Gaffari TUNÇ, Duygu YALINBAŞ YETER, Feyzanur KARAGÖZ, Emine Erva TECER, Senem AKKAN, Fatih KILIÇBAY

Evaluation of arterial stiffness between peritoneal dialysis and hemodialysis in patients with renal replacement therapy

Tufan GÜNAY, Dursun TOPAL, Suat AKGÜR

Effect of celecoxib on intra-abdominal sepsis-induced lung injury in rats

Cengiz DIBEKOGLU, Ejder Saylav BORA, Ebru EROĞLU, Guner YURTSEVER, Yiğit UYANIKGİL, Oytun ERBAŞ

Relationship between uric acid/ albumin ratio and coronary slow flow

Aykut DEMİRKIRAN, Cihan AYDIN

Comparison of frozen section accuracy with final pathology results in early clinical stage of endometrioid type endometrial cancer

Levent ÖZGEN, Gülten ÖZGEN

Comparison of nutritional adequacy in adult patients with acute respiratory distress syndrome with and without veno-venous extracorporeal membrane oxygenation: a single-center experience

Gülbahar ÇALIŞKAN, Nermin KELEBEK GİRGİN

The effect of perceived parental attitude score on symptoms of bipolar disorder and schizophrenia

Ece YAZLA, Unsal AYDİNOGLU, Elvan OZALP