Balo’s concentric sclerosis: a case report

Balo’s concentric sclerosis: a case report

Balo’s concentric sclerosis is a rare variant of multiple sclerosis which is characterized by lesions consistingrings of demyelination alternating with areas of relatively preserved myelin. These pathological changes arereflected by characteristic magnetic resonance imaging findings. We present the imaging findings of a case ofBCS who presented with an acute neurological disturbance, showed a dramatical recovery followingcorticosteroid therapy, and remained free of relapse for more than 1 year. Although previously considered as afulminant and fatal disease, characteristic MRI findings of Balo’s concentric sclerosis enable earlier diagnosisand treatment, and better prognosis.

___

  • [1] Hardy AT, Miller DH. Balo’s concentric sclerosis. Lancet Neurol 2014;13:740-746.
  • [2] Darke M, Bahador FM, Miller DC, Litofsky NS, Ahsan H. Balo’s concentric sclerosis: imaging findings and pathological correlation. JRCR 2013;7:1-8.
  • [3] Popescu BF, Lucchinetti CF. Pathology of demyelinating diseases. Annu Rev Pathol 2012;7:185-217.
  • [4] Karaarslan E, Altıntas A, Senol U, Yeni N, Dincer A, Bayindir C, et al. Balo’s concentric sclerosis: clinical and radiologic features of five cases. AJNR Am J Neuroradiol 2001;22:1362-7.
  • [5] Kavanagh EC, Heran MK, Fenton DM, Lapointe JS, Nugent RA, Graeb DA. Diffusion-weighted imaging findings in Balo’s concentric sclerosis. Br J Radiol 2006;79;e28-31.
  • [6] Ripellino P, Khonsari R, Stecco A, Filippi M, Perchinunno M, Cantello R. Clues on Balo’s concentric sclerosis evolution from serial analysis of ADC values. Int J Neurosci 2016;126:88- 95.
  • [7] Khiat A, Lesage J, Boulanger Y. Quantitative MRS study of Balo’s concentric sclerosis lesions. Magn Reson Imaging 2007;25:1112-5.
  • [8] Bolcean J, Acou M, Mertens K, Hallaert G, Van den Broecke C, Achten E, et al. Structural and metabolic features of two different variants of multiple sclerosis: a PET/MRI study. J Neuroimaging 2013;23:431-6.
  • [9] Scott T. Balo’s concentric sclerosis. Accessed on 28.4.2016 at http://www.medmerits.com/index.php/article/balo_concentric_sc lerosis/P5
The European Research Journal-Cover
  • ISSN: 2149-3189
  • Yayın Aralığı: 6
  • Başlangıç: 2015
  • Yayıncı: Prusa Medikal Yayıncılık Limited Şirketi
Sayıdaki Diğer Makaleler

Filiz TUNA, Hande ÖZDEMİR, Demirbağ Derya KABAYEL, Zeynep Banu DOĞANLAR

The alteration of first trimester screening markers in fresh and frozen-thawed blastocyst transfers

Ayşe Filiz Gökmen Karasu, Aynur Erşahin, Nur Dokuzeylül Güngör, Tuğba Gürbüz

Cardioprotective effect of vitamin D and melatonin on doxorubicin-induced cardiotoxicity in rat model: an electrocardiographic, scintigraphic and biochemical study

Serdar Savaş Gül, Hatice Aygün

Duygu KERİM, Aslıhan UZUNKULAOĞLU, Saime AY

Does laparoscopic appendectomy increase the risk of intra-abdominal abscess in children who have perforated appendicitis?

Fatih AKBIYIK, Günay EKBERLİ, Yusuf Hakan ÇAVUŞOĞLU

Kenan GÜVENÇ, Mustafa Kemal İLİK, Faik İLİK, Murat GÖNEN, Fatih KAYHAN

Effect of an adapted physical activity program on the morphological and physiological profile of hypertensive patients of University Clinics of Kinshasa

Teddy Bofosa, Betty Miangindula, Constant Nkiama, Godefroid Kusuayi, Nicaise Kiana

Comparing the effect of two different exercise types, mini-trampoline and fast-walking to gastrocnemius/soleus muscle elasticity by sonoelastrography

Tuba Tülay KOCA, Murat BAYKARA, Adnan DEMİREL, Ejder Berk

Increased P wave duration and dispersion is associated with catheter-related atrial fibrillation during electrophysiological study

Yahya Kemal İçen, Mevlüt Koç1, Hilmi Erdem Sümbül

Relationship between students’ performance on weekly task assessments and final practical exam at the preclinical restorative dentistry course

Muhammet Kerim Ayar