This study presents the domoic acid (DA), responsible from Amnesic Shellfish Poisoning (ASP), levels of plankton net samples in the Sea of Marmara during April, July and October 2019. Plankton net samples were collected from 13 stations, which were located close to the Istanbul metropolitan area, and along the east and southwest parts of the Sea of Marmara. DA measurements were done by high-performance liquid chromatography (HPLC), using the diode-array detection (detection limit (LOD): 0.108 µg mL−1). Twenty-two out of the 26 plankton net samples (84.6%) were found to contain DA during the study period and the concentrations varied between 0.22 and 3.45 µg mL−1. Possible relationships between physical parameters (salinitytemperature) and DA concentrations were investigated. DA production was mainly controlled by salinity (r:0.47, p
Bu çalışmada Nisan, Temmuz ve Ekim 2019 dönemlerinde Marmara Denizi’nden alınan plankton kepçe örneklerinde Amnezik Kabuklu Zehirlenmesi’ne (AKZ) neden olan denizel biyotoksin, domoik asit (DA), seviyeleri sunulmaktadır. Plankton kepçe örneklemeleri, Marmara Denizi’nin doğusunda, güneybatısında ve İstanbul metropol bölgesinin yakınında bulunan toplam 13 adet istasyondan yapılmıştır. Domoik asit ölçümleri, diode-array dedeksiyonu kullanılarak Yüksek Performanslı Sıvı Kromatografisi yöntemiyle gerçekleştirilmiştir (Belirleme limiti: 0,108 µg mL−1). Çalışma dönemi boyunca alınan toplam 26 adet plankton kepçe örneğinden 22’sinin (%84,6) DA içerdiği tespit edilmiş ve bu örneklerdeki konsantrasyon aralığı 0,22 – 3,45 µg mL−1 olarak belirlenmiştir. DA konsantrasyonları ile fiziksel parametreler (tuzluluk ve sıcaklık) arasındaki olası ilişkiler incelenmiş ve çalışma dönemi boyunca DA üretiminin genel olarak tuzluluk (r:0,47, p
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