Bahattin ÖZKUL, Fatih YENİHAYAT, Furkan URFALI, Nurşen YÜKSEL, Arzu ARSLAN

Difüzyon Tensör Görüntülemenin Primer Açık Açılı Glokom Hastalarının Görme Yollarındaki Tanısal Performansı

Amaç: Glokomlu hastalarda optik sinir (OS), optik trakt (OT) ve optik radyasyonda (OR) nörodejenerasyonun tespitinde difüzyon tensör görüntülemenin (DTG) tanı performasını değerlendirmek ve DTG parametreleri ile glokom evresi arasında uyumu belirlemek. Gereç ve Yöntem: Primer açık açılı glokomlu 33 hastanın (17 erkek, 16 kadın, 29-81 yaşında) 65 gözü ve 37 hastalığı bulunmayan gönüllünün 74 gözü çalışmaya dâhil edilmiştir. Tüm çalışmaya katılanlar optik koherens tomografinin de dâhil olduğu tam göz muayenesinden geçirilmiş olup Hodapp-Anderson-Parrish sınıflamasına göre evrelere ayrılmışlardır. 3T cihazla elde edilen görüntülerden otomatik olarak MD ve FA haritaları oluşturularak ortalama difüzivite (MD), fraksiyonel anizotropi (FA), radyal ve aksiyel difüzivite (RD ve AD) ölçümleri yapılmıştır. İstatistik analizi için SPSS kullanılmıştır. p

Anahtar Kelimeler:

Aksiyel difüzivite; AD, Difüzyon tensör görüntüleme; DTG, Fraksiyonel anizotropi; FA, glokom, ortalama difüzivite; MD, radyal difüzivite; RD

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