Fethiye AKGUL, Pınar ATABEY, Eren ZİLELİGİL

COVID-19 pnömonisi ile ilişkili bir uygunsuz antidiüretik hormon salınımı sendromu olgusu

Uygunsuz antidiüretik hormon salınımı sendromu (UADHSS), hastanede yatan hastalarda hiponatreminin en sık nedenlerinden biridir. Hiponatreminin etiyolojisinde birçok neden olmasından dolayı sebebinin bulunup tedavi edilmesinde güçlük yaşanabilmektedir. UADHSS’ye neden olabilecek birçok infeksiyon hastalığı bildirilmiştir. Bununla birlikte Koronavirüs 2019 hastalığı (COVID-19) ile ilişkili hiponatremi ve UADHSS son zamanlarda birkaç olgu raporunda belirtilmiştir. Bizim olgumuzda ise ilk hastaneye başvuru sırasında COVID-19 pnömonisinin klasik semptomları olan öksürük, nefes darlığı ve ateş şikâyeti, ikinci başvurusunda ise hiponatreminin klinik semptomlarından olan halsizlik, genel durum bozukluğu görülmekteydi. COVID-19 olan bir hastada hiponatremi ve UADHSS’nın görülebileceğini vurgulamayı amaçladık.

A case with the syndrome of inappropriate antidiuretic hormone secretion associated with COVID-19 pneumonia

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of the most common causes of hyponatremia in hospitalized patients. Since there are several etiologies of hyponatremia, it may be difficult to identify and treat the etiology. Several infectious diseases have been reported to cause SIADH. However, hyponatremia and SIADH induced by Coronavirus 2019 disease (COVID-19) have been reported in several recent case reports. However, our case admitted to hospital with the classic symptoms of COVID-19 pneumonia including cough, dyspnea and fever at his first admission, and with the clinical symptoms of hyponatremia, including weakness and general condition disorder at his second admission. Our aim is to emphasize that hyponatremia and SIADH may be observed in a COVID-19 patient.

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