Muharrem BAYRAK, Kenan ÇADIRCI, Emine KARTAL BAYKAN, Unsal AYDIN, Ayşe ÇARLIOĞLU

Graves hastalığından Hashimoto tiroiditine spontan dönüşüm: olgu sunumu

Graves hastalığı ve otoimmün tiroiditler, otoimmün etiyoloji ile oluştuğu gösterilmiş tiroid hastalıkları spektrumunun içinde yer alır. Tiroide karşı otoantikorların varlığı bilinmektedir ve tiroid tüm vücutda otoimmün hastalıkların en sık görüldüğü organdır. Ellerinde titreme, terleme ve çarpıntı şikayetleri ile başvuran 29 yaşında bayan hastaya laboratuar bulgular eşliğinde Graves hastalığı tanısı konularak anti-tiroid tedavi başlanıldı. Hasta iki yılın sonunda remisyona girdi. Remisyona giren hasta 18 ay anti-tiroid ilaç kullanımı olmadan ötiroid olarak takip edildi. 18. ayın sonunda rutin poliklinik kontrolünde Hashimoto tiroiditi geliştiği tespit edildi.

Anahtar Kelimeler:

Graves hastalığı, Hashimoto Hastalığı, otoantikorlar

Spontaneous conversion from Graves’ disease to Hashimoto’s thyroiditis: a case report

Graves’ disease and autoimmune thyroiditis are part of the spectrum of thyroid diseases known to develop with an autoimmune etiology. The presence of anti-thyroid autoantibodies is known, and the thyroid is the organ where autoimmune diseases are most commonly seen in the all body. A 29-year-old woman who admitted our clinic with tremor in the hands, sweating and palpitation was diagnosed with Graves’ disease with accompanying laboratory findings and was started on anti-thyroid therapy. The patient entered into remission at the end of 2 years. She was then regarded as euthyroid and followed-up for another 18 months without using anti-thyroid drugs. At the end of 18 months, Hashimoto’s thyroiditis was determined to have developed at routine polyclinic follow-up.

Keywords:

Graves’ disease, Hashimoto’s disease, autoantibodies,

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