Cetrimide-Chlorhexidine-Induced acute hepatic failure

Hydatid cystsarefrequently found in the liver and may be asymptomatic until growth occurs. Scolicidal agents, such as cetrimide-chlorhexidine, have been used safely in hydatid cyst surgery for many years. Here we presenta case of acute hepatic failure after the usage of the cetrimide-chlorhexidine solution during hepatic hydatid cyst surgery. To the best of our knowledge, this is the first such report in the literature.

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1. Caglar R, Yuzbasioglu MF, Bulbuloglu E, et al. In vitroeffectiveness of different chemical agents on scolices of hydatid cyst. J Invest Surg. 2008;21:71-5.

2. Tripathy S, Sasmal P, Rao PB, et al. Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst. Ann Card Anaesth. 2016;19:557-60.

3. Sathyanarayana MV, Shenoy MG, Pai VM, et al. Metabolic acidosis induced by cetrimide-chlorhexidine solution in hydatid cyst surgery. Indian J Gastroenterol. 1996;15:104.

4. Puj KS, Chauhan VF. Cetrimide induced metabolic acidosis: A rare intraoperative complication in a case of hydatid disease of liver. Int J Sci Res. 2014;5:1492-5.

5. Gilchrist DS. Chemical peritonitis after cetrimide washout in hydatid-cyst surgery. Lancet. 1979;2:1374.

6. Aydin C, Kayaalp C, Nessar G, et al. Is cetrimide-chlorhexidine risky for secondary sclerosing cholangitis? Adv Clin Exp Med. 2014;23:395-8.

7. Tozar E, Topcu O, Karayalcin K, et al. The effects of Cetrimide–Chlorhexidine combination on the Hepato-Pancreatico-Biliary system. World J Surg. 2005;29:754-8.

8. Kantar FU. Approach to elevated liver function tests. Klinik Tıp Bilimleri. 2017;5:30-8.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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