The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma

The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma

ABSTRACT Objective: The aim of this study is to investigate the effect of the preemptive use of plerixafor in patients with lymphoma and multiple myeloma which was administered as a preemptive single dose to the patients who were determined to have a CD34+ cell count of

___

  • Ljungman P, Bregni M, Brune M, et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009. Bone Marrow Transplant 2010;45:219-34. doi: 10.1038/ bmt.2009.141
  • Passweg JR, Baldomero H, Gratwohl A, et al. The EBMT activity survey: 1990-2010. Bone Marrow Transplant 2012;47:906-23. doi: 10.1038/bmt.2012.66
  • Arora S, Majhail NS, Liu H. Hematopoietic progenitor cell mobilization for autologous stem cell transplantation in multiple myeloma in contemporary era. Clin Lymphoma Myeloma Leuk 2019;19:200-5. doi: 10.1016/j.clml.2018.12.010
  • Mohty M, Hübel K, Kröger N, et al. Autologous haematopoietic stem cell mobilisation in multiple myeloma and lymphoma patients: a position statement from the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2014;49:865-72. doi: 10.1038/bmt.2014.39
  • Giralt S, Costa L, Schriber J, et al. Optimizing autologous stem cell mobilization strategies to improve patient outcomes: consensus guidelines and recommendations. Biol of Blood Marrow Transplant 2014;20:295-308. doi: 10.1016/j. bbmt.2013.10.013
  • Farina L, Spina F, Guidetti A, et al. Peripheral blood CD34+ cell monitoring after cyclophosphamide and granulocytecolony- stimulating factor: an algorithm for the pre-emptive use of plerixafor. Leukemia Lymphoma 2014;55:331-6. doi: 10.3109/10428.194.2013.802783
  • Ataca Atilla P, Bakanay Ozturk SM, Demirer T. How to manage poor mobilizers for high dose chemotherapy and autologous stem cell transplantation? Transfusion Apher Sci 2017;56:190- 8. doi: 10.1016/j.transci.2016.11.005
  • Wuchter P, Ran D, Bruckner T, et al. Poor mobilization of hematopoietic stem cells-definitions, incidence, risk factors, and impact on outcome of autologous transplantation. Biol Blood Marrow Transplant 2010;16:490-9. doi: 10.1016/j. bbmt.2009.11.012
  • Lee JL, Kim SB, Lee GW, et al. Collection of peripheral blood progenitor cells: analysis of factors predicting the yields. Transfus Apher Sci 2003;29:29-37. doi: 10.1016/s1473- 0502(03)00097-1
  • Paripati H, Stewart AK, Cabou S, et al. Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma. Leukemia 2008;22:1282-4. doi: 10.1038/ sj.leu.2405100
  • Olivieri A, Marchetti M, Lemoli R, et al. Proposed definition of ‘poor mobilizer’ in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo. Bone Marrow Transplant 2012;47:342-51. doi: 10.1038/bmt.2011.82
  • Shah EE, Young RP, Wong SW, et al. Impact of plerixafor use at different peripheral blood cd34(+) thresholds on autologous stem cell collection in patients with multiple myeloma. Blood Marrow Transplant 2020;26:876-83. doi: 10.1016/j. bbmt.2019.11.024
  • Douglas KW, Gilleece M, Hayden P, et al. UK consensus statement on the use of plerixafor to facilitate autologous peripheral blood stem cell collection to support high-dose chemoradiotherapy for patients with malignancy. J Clin Apher 2018;33:46-59. doi: 10.1002/jca.21563
  • Keating GM. Plerixafor: a review of its use in stem-cell mobilization in patients with lymphoma or multiple myeloma. Drugs 2011;71:1623-47. doi: 10.2165/11206.040.000000000- 00000
  • Cooper DL, Medoff E, Patel N, et al. Autologous stem cell mobilization in the age of plerixafor. Clin Lymphoma Myeloma Leuk 2016;16:411-6. doi: 10.1016/j.clml.2016.04.007
  • Spoerl S, Peter R, Wäscher D, et al. Patients’ outcome after rescue plerixafor administration for autologous stem cell mobilization: a single-center retrospective analysis. Transfusion 2017;57:115-21. doi: 10.1111/trf.13883
  • Gambell P, Herbert K, Dickinson M, et al. Peripheral blood CD34+ cell enumeration as a predictor of apheresis yield:an analysis of more than 1,000 collections. Blood Marrow Transplant 2012;18:763-72. doi: 10.1016/j.bbmt.2011.10.002
  • Szwajcer D, Jennings-Coutts A, Giftakis A, Wall DA. Identification of the CD34 enumeration on the day before stem cell harvest that best predicts poor mobilization. Transfusion 2011;51:587-90. doi: 10.1111/j.1537-2995.2010.02891.x
  • Sancho JM, Morgades M, Grifols JR, et al. Predictive factors for poor peripheral blood stem cell mobilization and peak CD34(+) cell count to guide pre-emptive or immediate rescue mobilization. Cytotherapy 2012;14:823-9. doi: 10.3109/14653.249.2012.681042
  • Costa LJ, Alexander ET, Hogan KR, Schaub C, Fouts TV, Stuart RK. Development and validation of a decision-making algorithm to guide the use of plerixafor for autologous hematopoietic stem cell mobilization. Bone Marrow Transplant 2011;46:64-9. doi: 10.1038/bmt.2010.78
  • Solá C, Maroto P, Salazar R, et al. Bone marrow transplantation: prognostic factors of peripheral blood stem cell mobilization with cyclophosphamide and filgrastim (r-metHuG-CSF): The CD34+ cell dose positively affects the time to hematopoietic recovery and supportive requirements after high-dose chemotherapy. Hematology (Amsterdam, Netherlands) 1999;4:195-209. doi: 10.1080/10245.332.1999.11746443
  • Worel N, Fritsch G, Agis H, et al. Plerixafor as preemptive strategy results in high success rates in autologous stem cell mobilization failure. J Clin Apher 2017;32:224-34. doi: 10.1002/jca.21496
  • Micallef IN, Sinha S, Gastineau DA, et al. Cost-effectiveness analysis of a risk-adapted algorithm of plerixafor use for autologous peripheral blood stem cell mobilization. Blood Marrow Transplant 2013;19:87-93. doi: 10.1016/j. bbmt.2012.08.010
  • Vishnu P, Roy V, Paulsen A, Zubair AC. Efficacy and costbenefit analysis of risk-adaptive use of plerixafor for autologous hematopoietic progenitor cell mobilization. Transfusion 2012;52:55-62. doi: 10.1111/j.1537-2995.2011.03206.x
Marmara Medical Journal-Cover
  • ISSN: 1019-1941
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1988
  • Yayıncı: Marmara Üniversitesi
Sayıdaki Diğer Makaleler

Healthy life-style behaviors and related factors among Turkish primary health care professionals

Belgin ORAL, Nergiz SEVINC, Burcu KORKUT

Evaluation of autonomic nervous system functions by using tilt table test and heart rate variability in epileptic children

Azad REDJEPOV, Sinem ALTUNYUVA USTA, Yuksel YILDIRIM, Figen AKALIN

Effect of whey protein derivatives on cell viability, cell migration and cell cycle phases in MCF-7 cells

F. Tutku AKSOY, Ayse Mine YILMAZ, Gokhan BICIM, A. Suha YALCIN

The failure on the effectiveness of formalin on cadaver disinfection and alternative methods

Ozgur YANILMAZ, Mehmet Mucahit GUNCU, Mehmet Burak AKSU, Mazhar OZKAN, Umit Suleyman SEHIRLI

Effect of angiotensin receptor-neprilysin inhibitor treatment on erectile dysfunction in heart failure with a reduced ejection fraction

Sena SERT, Emre KARABAY, Baris GUNGOR, Ozlem YILDIRIMTURK

Glaucoma awareness in Family Health Centers

Miray SANCAKTAR DEMIROZ, Seyhan HIDIROGLU, Dilajla ORAOVCANIN, Merve AKBAS, Annisha Condace SKINNER, Sumeyye KARAPINAR, Ayse SARI, Melda KARAVUS

Can plasma fibrinogen level predict bone marrow fibrosis?

Yildiz IPEK, Ayse Nilgun KUL

Health behavior and health needs of first-year medical and health sciences students

Kamer GUR, Saime EROL, F. Esra GUNES, Serap CIFCILI, K. Burcu CALIK, Aysel Yildiz OZER, Ilksan DEMIRBUKEN, M. Gulden POLAT, Cigdem APAYDIN KAYA

The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma

Ayse UYSAL, Mehmet Ali ERKURT, Irfan KURU, Emin KAYA, Ilhami BERBER, Ahmet SARICI, Soykan BICIM, Ahmet KAYA, Emine HIDAYET

Medical students’ knowledge of the disease, frequency of depression, anxiety, stress symptoms, and related factors in the COVID-19 pandemic: A web-based questionnaire

Esra CINAR TANRIVERDI, Mustafa BAYRAKTAR, Suat SINCAN, Kamber KASALI, Yasemin CAYIR, Mine SAHINGOZ, Zulal OZKURT