SPİNAL ANESTEZİDE SEDASYON AMAÇLI UYGULANAN DEKSMEDETOMİDİNİN YÜKLEMELİ VE YÜKLEMESİZ İNFÜZYONUNUN HEMODİNAMİ VE SEDASYON ÜZERİNE ETKİLERİNİN RETROSPEKTİF İNCELENMESİ

AMAÇ: Bu çalışmanın amacı rejyonel anestezide sedasyon amaçlı uygulanan deksmedetomidinin spinal anestezide yüklemeli ve yüklemesiz infüzyonunun hemodinami ve sedasyon üzerine etkilerinin retrospektif olarak karşılaştırılmasıdır.

EVALUATION OF THE EFFECTS OF DEXMEDETOMIDINE INFUSION WITH OR WITHOUT PRELOADING THAT IS APPLIED BY THE AIM OF SEDATION ON SPINAL ANAESTHESIA ON HEMODINAMI AND SEDATION RETROSPECTIVELY

OBJECTIVE: The aim of this study is to compare the effects of infusion of dexmedetomidine in spinal anaesthesia with or without preloading that is applied by the aim of sedation on regional anaesthesia on sedation and hemodinamia retrospectively.MATERIAL AND METHODS: The medical and anaesthesia records of total 60 patients were evaluated retrospectively that lower abdominal and extremity surgery was applied with spinal anaesthesia and that dexmedetomidine infusion was applied for the aim of sedation between November 2003 - January 2015. The patients were divided into two groups as dexmedetomidine infusion with preloading; Group A (n=40) and dexmedetomidine infusion without preloading; Group B (n=20).The hemodynamic values Heart Rate (HR), Mean Arterial Pressure (MAP) and Ramsey Sedation Score (RSS) were evaluated on examined cases.RESULTS: The HR was decreased statistically significantly in Group A from the 10th minutes of the spinal anaesthesia to the 50th minutes of operation; and decreased statistically significantly from 20th minutes of the spinal anaesthesia to 50th minutes of operation. MAP was decreased statistically significantly according to control values in all time intervals from 15th minutes of spinal anaesthesia to 50th minutes of operation in Group A and from 10th minutes of spinalanaesthesia to 50th minutes of operation in Group B.The RSS values were found statistically significantly different between two groups on 5th, 25th, and 30th minutes. CONCLUSIONS: It is observed retrospectively that the proper sedation level can be reached without dexmedetomidine preloading on spinal anaesthesia applied cases by minimising hemodynamic instability.

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