Sırrı AVKİ, KÜRŞAD YİĞİTARSLAN, MEHMET ÇAĞRI KARAKURUM

Buzağılarda vitamin A kullanımına dikkat: sırtlan hastalığı

İlk kez 1975 yılında Fransa’da rapor edilen sırtlan hastalığı, genç sığırların özellikle pelvik ekstremitelerinde lokalize olan bir iskelet gelişim bozukluğu olarak tanımlanmaktadır. Pelvik ekstremiteleri kısa kalan sığırların yandan bakıda tıpkı bir sırtlan gibi görünmesine yol açan bu hastalığın nedeni, 1990’lı yılların sonuna kadar aydınlatılamamış ve birçok etiyolojik hipotez ortaya atılmıştır. Buzağılarda yapılan deneysel araştırmalar, sırtlan hastalığına yol açan asıl nedenin A hipervitaminozisi olduğunu ve bu hastalığın, çocuklarda yüksek dozlarda vitamin A kullanılmasına bağlı olarak gelişen fizeal obliterasyon ile benzer olduğunu ortaya koymuştur. Bu derlemede, günümüze kadar dünyanın değişik ülkelerinden rapor edilen sırtlan hastalığı olguları ve buzağılarda yapılan deneysel çalışmalar değerlendirilerek, hipervitaminozis A ile büyüme plaklarının erken kapanması arasındaki ilişkiye ve buzağılarda bilinçsiz A vitamini uygulamalarının tehlikesine dikkat çekildi.

Anahtar Kelimeler:

pelvis, sığır, buzağı, A vitamini fazlalığı, retinol, iskelet gelişimi

Care for vitamin A application in calves: Hyena disease

Hyena disease which was first reported in France in 1975 is considered as a disorder of skeletal development, especially localized in the pelvic limbs of young cattle. The hind limbs of the cattle shortened in this deformity and led the animal to have an appearance resembling that of a hyena in side view. The cause was unknown until the end of the 1990s and several etiological hypotheses were suggested. Experimental studies on calves demonstrated that the main cause of hyena disease is hypervitaminosis A and the deformity is similar to physeal obliteration of children due to overdoses of vitamin A. In this paper by reviewing the cases of hyena disease reported from different countries and experimental studies on calves, we draw attention to the relationship between hypervitaminosis A and premature closure of epiphyseal growth plates and the danger of uncontrolled vitamin A applications in calves.

Keywords:

pelvis, cattle, calves, vitamin A excess, retinol, skeletal development,

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