Hülya KULA, Zeynep GÜNAY UÇMAK, İsmail KIRŞAN, Gülay YÜZBAŞIOĞLU ÖZTÜRK, Ahmet GÜLÇUBUK

Clinicopathological evaluation of vaginal leiomyoma and ovarian luteoma in a bitch

A 7-years-old female Golden Retriever dog was presented to the clinic with a multilobular mass protruding from the vulva. On clinical examination, the mass was observed on the circumference of the vaginal canal. The owner reported not noticing a pro-estrous bleeding for a year. On vaginal cytology, parabasal cells, intermediate cells, neutrophil infiltration and clumps of bacteria were determined. Mild anemia, severe leukocytosis and high MPV value were detected. As a treatment, vaginal mass was totally extirpated by partial vaginectomy and subsequently ovariohysterectomy were performed to avoid the re-occurrence of the vaginal tumor. Both vaginal mass and ovariohysterectomy materials were histopatologically examined. Benign tumors were diagnosed which were vaginal leiomyoma and bilateral ovarian luteoma. It was concluded that histopathological analysis of every surgically removed tissue should be performed in order not to miss a tumorous condition even if it does not show any symptoms.

Keywords:

Bitch, ovarian luteoma, vaginal leiomyoma,

PDF

___

Aydın, D., Olgun Erdikmen, D., Ülgen, S., Demirutku, A., & Durmuş, D. (2011). Kedi ve Köpeklerde Paraneoplastik Sendromlar. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 8(2), 127-137. Retrieved from https://dergipark.org.tr/tr/pub/ercivet/issue/5826/77479
Çoban, T., Günay Uçmak, Z., Kılıçarslan, M. R., & Erdoğan Bamaç, Ö. (2021). Evaluation of complete blood count in bitches with ovarian tumors: A preliminary study. Journal of Istanbul Veterinary Sciences, 5(1), 1-5. Doi: 10.30704/http-www-jivs-net.837033
Ferré-Dolcet, L., Romagnoli, S., Banzato, T., Cavicchioli, L., Di Maggio, R., Cattai, A., Berlanda, M., Schrank, M., & Mollo, A. (2020). Progesterone-responsive vaginal leiomyoma and hyperprogesteronemia due to ovarian luteoma in an older bitch. BMC Veterinary Research, 16(1), 284. Doi: 10.1186/s12917-020-02507-z
Ichimura, R., Shibutani, M., Mizukami, S., Suzuki, T., Shimada, Y., & Mitsumori, K. (2010). A case report of an uncommon sex-cord stromal tumor consisted of luteal and sertoli cells in a spayed bitch. The Journal of Veterinary Medical Science, 72(2), 229–234. Doi: 10.1292/jvms.09-0235.
MacLachlan, N.J., & Kennedy, P.C. (2002). Tumors of the genital system, In: Tumors in domestic animals, edited by Meuten, D.J., 4th ed. Iowa State University Press, Ames, IA. 1(2):547-573.
McEntee M.C. (2002). Reproductive oncology. Clinical Techniques in Small Animal Practice,3, 133-149. Doi: 10.1053/svms.2002.34642
Moris, J., & Dobson, J., (2001). Small Animal Oncology, 1st Ed., Iowa State University Press, Iowa pp.166-167.
Moulton, J. E. (1990). Tumors of the genital system. In: Tumors of Domestic Animals. 3th ed. pp. 497-517, University of California Press, Berkeley, CA.
Namazi, F., Hasiri, M.A., Nikahvar, B., Khafi, M.S.A., & Kish, G.F. (2015). Clinicopathological and immunohistochemical characteristics of ovarian luteoma associated with endometrial hyperplasia in a bitch. Comparative Clinical Pathology, 24, 705–707. Doi: 10.1007/s00580-014-2043-2
Nelissen, P, & White, R.A.S. (2012). Subtotal Vaginectomy for Management of Extensive Vaginal Disease in 11 dogs. Veterinary Surgery, 41(4), 495–500. Doi: 10.1111/j.1532-950X.2011.00948.x.
Salomon, J. F., Deneuche, A., & Viguier, E. (2004). Vaginectomy and urethroplasty as a treatment for non-pedunculated vaginal tumours in four bitches. The Journal of Small Animal Practice, 45(3), 157–161. Doi: 10.1111/j.1748-5827.2004.tb00219.x.
Singh, K., Bodh, D., Gopinathan, A., Mohsina, A., & Sangeetha P. (2014). A case of concurrent inguinal hernia and vaginal leiomyoma in a bitch successfully treated surgically. Research Journal for Veterinary Practitioners, 2 (1), 1-4. Doi: 10.14737/JOURNAL.RJVP/2014/2.1.1.4
Yamini, B., VanDenBrink, P. L., & Refsal, K. R. (1997). Ovarian steroid cell tumor resembling luteoma associated with hyperadrenocorticism (Cushing's disease) in a dog. Veterinary Pathology, 34(1), 57–60. Doi: 10.1177/030098589703400112
Yılmaz, R., Özyiğit, M.Ö., & Akkoç, A. (2017). Bir köpekte tek taraflı luteoma olgusu. Uludag Universitesi Veteriner Fakültesi Dergisi, 36(1,2), 33-35. Doi: 10.30782/uluvfd.405642