Does affect combination of surgery with anti-fungal therapy prolong life a mucormycosis of sino-nasal? A Case Report
Does affect combination of surgery with anti-fungal therapy prolong life a mucormycosis of sino-nasal? A Case Report
Acute invasive fungal rhinosinusitis (AIFRS) is a rapidly progressive disease, which usually develops in patients with uncontrolled diabetes mellitus (DM) and those thatare immuno compromised.Mucor, Rhizopus, Absidia, Rhizomucor, and other mucorales fungi that belong to thedivision Zygomycota, or Aspergillus species that belong to the division Ascomycota, may be responsible for this disease. AIFRS exhibits high rates of mortality and morbidity, and prognosis of the disease mandates early diagnosis and treatment. Treatment includes immediate surgical intervention, systemic antifungal therapy, and quick treatment of the underlying systemic disease. Before the advent of amphotericin- B, mortality rates were as high as 90 percent. However, they have been reduced to 15 to 50 percent with the combined use of surgery and amphotericin-B. In this report, we present a case of mucormycosis of the rhino-orbital area treated with endoscopic sinus surgery, a medial maxillectomy with incomplete excision of the palate, and liposomal amphotericin B. The aim of this case report is to show that early surgery with medical therapy and regular follow-up could decrease mortality and increase life expectancy
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- deShazo RD, O’Brien M, Chapin K, et al (1997); A new classification and diagnostic criteria for invasive fungal sinusitus. Arch Otolaryngol Head Neck Surg 123:1181-1188.
- Richardson MD, Kahkola PK, Shankland GS(2003). Rhizopus, Rhizomucor, Absidia, and other agents of systemic and subcutaneous zygomycosesIn: Murray PR, Baron EJ, Jorgensen JH, et al, eds. Manual of Clinical Microbiology.
- Washington DC: ASM Press; pp 1761– 1780.
- Kontoyiannis DP, Lewis RE(2010) Agents of mucormycosis and Entomophthoramycosis. In: Mandell GL, Bennett
- GE, Dolin R, eds. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Churchill Livingstone; pp 3257-3269.
- Kontoyiannis DP, Wessel VC, Bodey GP, Rolston KV(2000) Zygomycosis in the 1990s in a tertiary-care cancer center. Clin Infect Dis 30(6):851-856.
- Scully C, OP de almeida, Sposto MR(1997)The deep mycoses in HIV infection Oral Dis 3(supply.1):200-207.
- Brandwein M. Histopathology of sinonasal fungal disease (1993) Otolaryngol Clin North 26: 949-81.
- Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP(2012) Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis. Feb 54 :23-34.
- Han DH, An SY, Kim SW, et al(2007) Primary and secondary fungal infections of the paranasal sinuses: clinical features and treatment outcomes. Acta Otolaryngol Suppl 555: 78 -82.
- Batra PS, Lanza DC(2005) Endoscopic power-assisted orbital exenteration. Am J Rhinol 19: 297-301.
- Spellberg B, Edwards Jr J, Ibrahim A (2005) Novel perspectives on mucormycosis: pathophysiology, presentation and management. Clin Microbiol Rev18: 556-569.
- Roden MM, Zaoutis TE, Buchanan WL, et al(2005) Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 41:634-653.
- Kasapoglu F, Coskun H, Ozmen OA, Akalın H, Ener B (2010) Acute invasive fungal rhinosinusitis: evaluation of patients treated with endonasal or open surgical procedures. Otolaryngol Head Neck Surg 143: 614-620.
- Arda B, Erdem A, Sipahi OR, Isıkgoz Tasbakan M, Pullukcu H,Ceylan N, et al(2011) [Mucormycosis: retrospective evaluation of 12cases]. Mikrobiyol Bul 45: 504-511.
- Skiada A, Lanternier F, Groll AH, Pagano L, Zimmerli S, Herbrecht R(2012) Diagnosis and treatment of mucormycosis in patients with haematological malignancies: guidelines from the 3rd European Conference on
- Infections in Leukemia (ECIL 3). Haematologica. 492-504. Gamaletsou MN, Sipsas NV, Roilides E, Walsh TJ(2012) Rhino-orbital-cerebral mucormycosis. Curr Infect Dis Rep. 4:423-434.
- Johnson JB, Affolter KE, Samadder NJ(2012) A Rare Cause of Hematochezia: Colon Mucormycosis. Clin
- Gastroenterol Hepatol, A22. Kontoyiannis DP, Lewis RE (2011) How I treat mucormycosis. Blood. 118:1216-1224.
- Spellberg B, Ibrahim A, Roilides E, et al(2012) Combination therapy for mucormycosis: why, what, and how?. Clin Infect Dis. 54:73-78.
- E. Kazak , E. Aslan , H. Akalın, O. Saraydaroglu , B. Hakyemez , L. Erisen¸ et al (2013)A mucormycosis case treated with a combination of caspofungin and amphotericin B. J Mycol Med 23:179-184.
- Turner EK, Samuel R (2004) A patient with cerebral zygomycosis cured with liposomal amphotericin B, caspofungin and ciprofloxacin without intracranial surgery. Infect Dis Clin Pract12: 38-40.
- ISSN: 2146-6033
- Yayın Aralığı: Yılda 2 Sayı
- Başlangıç: 2011
- Yayıncı: Veysi AKPOLAT