Mikdat BOZER, Asli KOKTENER, Murat Ozgur KİLİC, Nur ARSLAN, Ahmet TURKAN

Synchronous tumors: clear cell carcinoma of pancreas and gastrointestinal stromal tumor of stomach

Berrak hücreli karsinom, böbrek, over, akciğer ve tiroid karsinomlarının görece sık görülen bir varyantı olmasına karşın, bu tümör nadiren pankreastan kaynaklanmaktadır. Öte yandan, gastrointestinal stromal tümörler, gastointestinal sistemi etkileyen en sık mezenkimal tümörlerdir ve sıklıkla mide ve ince barsaklarda yerleşirler. Bu yazıda, sağ üst kadran ağrısı, sarılık, bulantı ve kusma ile başvuran 76 yaşındaki kadın hastada mide yerleşimli gastrointestinal stromal tümör ile birlikte olan pankreas berrak hücreli karsinom olgusu sunuyoruz. Senkron gastrointestinal stromal tümör ve pankreatik adenokarsinom vakaları literatürde nadiren bildirilmiştir. Bildiğimiz kadarıyla bu olgu, mide gastrointestinal stromal tümör ile pankreas adenokarsinomu berrak hücreli varyantı birlikteliği ile ilgili literatürdeki ilk vakadır

Senkron tümörler: pankreas berrak hücreli adenokarsinomu ve mide gastrointestinal stromal tümör

Although clear cell carcinoma is a common variant of carcinoma of kidney, ovary, thyroid and lung, this tumor rarely originates from the pancreas. On the other hand, gastrointestinal stromal tumors represent the most usual mesenchymal tumors affecting the gastrointestinal tract, and are mostly located in the stomach and small bowel. In this paper, we report a clear cell variant of pancreas adenocarcinoma combined with gastrointestinal stromal tumor of the stomach in a 76-year-old woman who presented with right upper quadrant pain, jaundice, nausea and vomiting. Synchronous appearance of gastrointestinal stromal tumors and pancreatic adenocarcinoma has been rarely reported. To our knowledge, this is the first report about clear cell variant of pancreas adenocarcinoma combined with gastric gastrointestinal stromal tumor in the literature

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