Stabil Koroner Arter Hastalığı Olan Şizofreni Hastalarında Monosit/Yüksek Yoğunluklu Lipoprotein (MHR) Oranının Öngördürücülüğü

Amaç: Bu çalışmada stabil koroner arter hastalığı olan şizofreni hastalarında (SKAH-Ş) monosit/yüksek yoğunluklu lipoprotein oranının (MHO) tanıda öngördürücü değerinin olup olmadığını araştırmayı amaçladık. Gereç ve yöntem: Bu kesitsel çalışmaya toplam 281 katılımcı alındı. Katılımcıların 85'ine şizofreni ve stabil koroner arter hastalığı (Grup 1), 92'sine ise sadece şizofreni (Grup 2) tanısı konuldu. Kontrol grubundaki 104 katılımcının (Grup 3) ise hiçbir hastalığı yoktu. Bulgular: MHO grup 1'de en yüksek iken grup 2'de grup 3'e göre daha yüksekti (grup 1: 18.91 (13.38-23.60); grup 2: 13.68 (11.11-16.66); grup 3: 12.50 (9.13-15.68); her iki karşılaştırma için p

Anahtar Kelimeler:

Koroner arter hastalığı, şizofreni, monosit/yüksek yoğunluklu lipoprotein oranı, inflamasyon, oksidatif stres

Predictive Value of Monocyte to High-Density Lipoprotein Cholesterol Ratio (MHR) in Schizophrenia Patients with Stable Coronary Artery Disease

Aim: We aimed to investigate whether monocyte/high density lipoprotein ratio (MHR) has a predictive value in patients with schizophrenia (SP) and in schizophrenia patients with stable coronary artery disease (SPCAD). Material and Method: A total of 281 participants were enrolled in this cross-sectional study. Of the participants, 85 (Group 1) were diagnosed schizophrenia and stable coronary artery disease, and 92 (Group 2) were diagnosed only schizophrenia. 104 (Group 3) participants in the control group had no disease. Results: MHR was highest in group 1 and higher in group 2 than in group 3 (18.91 (13.38-23.60) vs. 13.68 (11.11-16.66) vs. 12.50 (9.13-15.68), respectively; p

Keywords:

schizophrenia, Coronary artery disease, monocyte to high-density lipoprotein ratio, inflammation, oxidative stress,

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