Parakuat intoksikasyonu: olgu sunumu
Zararlı bitkileri öldürmek amacıyla (herbisit) yaygın olarak kullanılan parakuat insanlarda da kazara ya da intihar amaçlı kullanıldığında yüksek oranda morbidite ve mortaliteye neden olmaktadır. İntihar amaçlı yüksek miktarda parakuat alım öyküsü sonrasında başlangıçta asemptomatik olup takiplerinde gastrointestinal, böbrek ve karaciğer etkilenmesi gelişen ve acil serviste takip ve tedavisi yapılan 23 yaşında genç bayan olguyu sunmaktayız. Ciddi parakuat zehirlenmesi olan hastalar alımından sonra asemptomatik olabilir, ancak birkaç saat içinde hızla bozulabilir. Bu nedenle parakuat alımlarında asemptomatik olsa bile hasta karaciğer, böbrek ve akciğer etkileri açısından uzun süre takip edilmelidir.
Paraquat intoxication: a case report
Paraquat, a widely used herbicide, causes high morbidity and mortality in people when taken accidentally or for suicidal intent. In this study our aim is to present the treatment and follow up of a 23 years old young lady after a history of suicide attempt in the emergency department after taking large amount of paraquat. The patient was initially asymptomatic and in follow up care gastrointestinal, renal and liver toxicity developed. Patients with severe paraquat poisoning may be asymptomatic after ingestion, but may deteriorate rapidly within a few hours. Therefore, in the case of taking high dose paraquat, the patient needs long term follow up for liver, kidney and lung effects even if he is asymptomatic.
___
- 1.Robey WC, Meggs WJ. Insecticides, Herbicides, Rodenticides
In: Tintinalli JE, Kelen GD, Stapczynki JS, eds. Emergency
Medicine: A Comprehensive Study Guide. 8th ed. New York,
NY: McGraw&Hill; 2010:1302-3
- 2. Onyeama HP, Oehme FW. A literature review of paraquat
toxicity. Vet Hum Toxicol 1984;26(6):494-502
- 3. Sittipunt C. Paraquat poisoning. Respir Care 2005;50(3):383-5
- 4. Sabzghabaee AM, Eizadi-Mood N, Montazeri K, Yaraghi A,
Golabi M. Fatality in paraquat poisoning. Singapore Med J
2010;51(6):496-500
- 5. Vale JA, Meredith TJ, Buckley BM. Paraquat poisoning:
clinical features and immediate general management. Human
Toxicol 1987;6(1):41-7
- 6. Dinis-Oliveira RJ, Sarmento A, Reis P, Amaro A, Remião F,
Bastos ML, et al. Acute paraquat poisoning: report of a survival
case following intake of a potential lethal dose. Pediatr Emerg
Care 2006;22(7):537-40
- 7. Klein-Schwartz W, Smith GS. Agricultural and horticultural
chemical poisonings: mortality and morbidity in the United
States. Ann Emerg Med 1997;29(2):232-8
- 8. Choi Y, Cho K, Yoon S, Lee H, Choi Y. A case of paraquat
intoxication caused by intravenous injection. Am J Emerg Med
2008;26(7):836.e3-4
- 9. Kim SJ, Gil HW, Yang JO, Lee EY, Hong SY. The clinical
features of acute kidney injury in patients with acute paraquat
intoxication. Nephrol Dial Transplant 2009;24(4):1226-32.