Procalcitonin and C-reactive Protein Measurements in the Early Diagnosis of Surgical Site Infections After Cesarean Section

Objective: We aimed to determine whether serum procalcitonin (PCT) levels measured after cesarean section weresuperior to the levels of other infection markers in the early diagnosis of surgical site infection (SSI).Materials and Methods: The present study was conducted with consecutive 249 patients who underwent electiveprimary cesarean delivery in our obstetrics clinic of a Private Hospital between November 2018 and April 2019.Measurements of serum PCT, C-reactive protein (CRP) and white blood cell (WBC) counts were performed at thepostoperative 6th, 12thand 24th hours. The participating patients were examined for SSI on the postoperative 2nd,4hand7th days.Results: Of the participants, 15 (6%) developed surgical site infections, PCT was the most sensitive and specificmarker of the SSI. Area under the curve (AUC) for PCT in predicting the SSI was 0.912 (95% CI: 0.79-1) and cutoffpoint was 0.099 ng/ml with a sensitivity of 93.3%, and specificity of 92.3% (p

Sezaryen Sonrası Cerrahi Alan Enfeksiyonlarının Erken Dönem Tanısında Prokalsitonin ve C-reaktif protein Ölçümlerinin Yeri

Giriş ve Amaç: Sezaryen sonrası ölçülen serum prokalsitonin (PKT) düzeylerinin cerrahi alan enfeksiyonu (CAE)'ların erken tanısında diğer enfeksiyon belirteçlerine gore üstün olup olmadığını belirlemeyi amaçladık. Gereç ve Yöntemler: Bu çalışma, Kasım 2018 ile Nisan 2019 tarihleri arasında Özel Hastane kadın doğum kliniğimizde elektif primer sezaryen ile doğum yapan 249 hasta üzerinde gerçekleştirildi. Postoperatif 6., 12. ve 24. saatlerde serum PKT, C-reaktif protein (CRP) ve beyaz kan hücresi sayılarının ölçümleri yapıldı. Hastalar postoperatif 2., 4. ve 7. günlerde CAE açısından incelendi. Bulgular: Katılımcıların 15'inde (%6) cerrahi alan enfeksiyonu gelişti. PKT, CAE'ların en hassas ve spesifik belirleyicisiydi. PKT için CAE'nın öngörülmesinde eğri altındaki alan 0.912 (% 95 CI: 0,79-1) ve kesme noktası 0,099 ng / ml , % 93,3 duyarlılık ve % 92,3 özgüllük idi (p

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