Ertuğrul KURTOĞLU, Tolga ÇAKMAK, Fatih GÜNGÖREN, Şıho HİDAYET, Güney SARIOĞLU

DİKLOFENAK POTASYUMUN ORAL ALIMINA BAĞLI KOUNİS SENDROMU: OLGU SUNUMU

Allerjik reaksiyonlar, koroner spazm, akut stent trombozu veya inflamatuar sitokinlerin salınması sonucu koroner plak rüptürü yoluyla akut koroner sendroma neden olabilirler. Bu klinik antite Kounis Sendromu olarak adlandırılır. 64 yaşında erkek hasta göğüs ağrısı, nefes darlığı, bulantı ve kusma şikayetleri ile hastanemiz acil servisine başvurdu. Başvuru öncesinde baş ağrısı için oral yolla diklofenak kullandığı tespit edildi. Elektrokardiyografisinde(EKG) lateral derivasyonlarda STsegment yükselmesi izlendi. Acil koroner anjiyografide koroner damarlar normaldi. Hastaya anafilaktik reaksiyon teşhisi kondu. Anafilaksi başarıyla tedavi edildikten sonra, ST-segment yükselmeleri çözüldü. Klinisyenler bu sendromun hızlı tanı ve uygun tedavi için farkında olmalıdır.

Kounis Syndrome Due to Oral Intake of Diclofenac Potassium: A case report

Allergic reactions may cause acute coronary syndrome by coronary spasm, acute stent thrombosisor coronary plaque rupture via releasing of inflammatory cytokines. This clinical entity istermed as Kounis Syndrome. We encountered a 64-year-old male who admitted to emergencydepartment of our hospital with complaints of chest pain, shortness of breath, nausea andvomiting. Before the application, it was found that he used diclofenac orally for headache. Hiselectrocardiography(ECG) showed ST-segment elevations in lateral derivations. Emergencycoronary angiography revealed normal coronary vessels. He was eventually diagnosed with ananaphylactic reaction. After successful treatment of anaphylaxis, ST-segment elevations resolved.Clinicians should be aware of this syndrome for promt recognition and proper treatment.

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