Zafer ORHAN, Murat ALPER, Mehmet DEMİRKAYA, Kutay ÖZTURAN

Ekstrakorporeal şok dalgası tedavisinin tendon dokusuna etkileri: Sıçanlarda deneysel çalışma

Amaç: Son yıllarda gündeme gelen ekstrakorporeal şok dalgası tedavisi, kaynama gecikmesi, omzun kalsifiye tendiniti, tenisçi dirseği ve plantar fasyitis tedavisinin de aralarında olduğu bir çok hastalıkta kullanılmaktadır. Bu tedavinin tendon ve komşu dokulara muhtemel zararlı etkilerini ortaya koymak amacıyla sıçanlarda deneysel bir araştırma gerçekleştirdik. Çalışma planı: Otuz iki adet Wistar albino cinsi sıçan sekizerlik dört gruba ayrıldı. İlk üç deney grubuna sırasıyla 14 kV’ lik 1000, 14 kV’lik 1500 ve 18 kV’lik 2000 şok dalgası uygulandı. Dördüncü grup kontrol grubunu oluşturdu. Bu enerji şiddeti ve şok dalgası uygulamasının sıçanların aşil tendonlarına etkisi araştırıldı. Sonuçlar: 14 kV 1000 şok ve 14 kV 1500 şok gruplarında belirgin bir histopatolojik değişiklik görülmedi. 18 kV 2000 şok uygulanan grupta ise liflerde hafif derecede dizilim bozukluğu ve seyrek lenfositler görüldü. Çıkarımlar: Histopatolojik değişikliklerin 18 kV 2000 şok dalgasından itibaren gözlenmesi nedeniyle, yüksek enerjili şok dalgası uygulamalarında olası doku değişikliklerini göz önüne almak gerekir.

Anahtar Kelimeler:

Litotripsi, Sıçanlar, Tendon yaralanmaları, Aşil tendon, Hastalık modelleri, hayvan

The effect of extra-corporeal shock wave therapy (ESWT) on the albino rat tendon tissue

Objectives: In recent years extracorporeal shock wave therapy has been reported to be useful in the treatment of a number of diseases including delayed bony union, calcifying tendinitis of the shoulder, tennis elbow, and plantar fascitis. In order to assess possible detrimental effects of this therapy on tendons and neighboring tissues a prospective study was carried out with rats. Methods: Thirty-two Wistar albino rats were equally divided into four groups. The first three groups were administered 1000 shock waves at 14 kV, 1500 at 14 kV, and 2000 at 18 kV, respectively. The fourth group included the controls. The effects of different shock waves at different power set-ups on rat achille tendons were investigated. Results: A marked histopathologic change was not observed with 1000 and 1500 shock waves at 14 kV. Mild disorganization in the leafs of collagen tissue and rare lymphocytes were detected with 2000 shock waves at 18 kV. Conclusion: Observation of histopathologic changes with 2000 shock waves at 18 kV suggest that adverse tissue changes should be considered when applying high energy shock waves.

Keywords:

Lithotripsy, Rats, Tendon Injuries, Achilles Tendon, Disease Models, Animal,

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